Paloxi 0.5 mg (Capsule)
Unit Price: ৳ 22.00 (2 x 10: ৳ 440.00)
Strip Price: ৳ 220.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Palonosetron |
| Company | Beacon pharmaceuticals plc |
| Also available as |
Indications
- Acute and delayed nausea and vomiting
- Uncontrolled nausea and vomiting
- Chemotherapy-induced nausea and vomiting (CINV)
- Radiotherapy-induced nausea and vomiting (RINV)
- Post-operative & Post-discharge nausea and vomiting (PONV & PDNV)
Pharmacology
- 5-HT3 receptor antagonist
- Strong binding affinity for 5-HT3 receptor
- Little or no affinity for other receptors
- Influence on postoperative nausea and vomiting
- Inhibition of serotonin actions
- Pharmacokinetics: linear dose-proportional, volume of distribution, metabolization, excretion, half-life, binding affinity
Dosage & Administration
- Usual dosage for adults and children
- Administration via tablet and intravenous
- Specific dosages for different types of nausea and vomiting
Interaction
- Safety with corticosteroids, analgesics, antiemetics/antinauseants, antispasmodics
- No inhibition of antitumor activity of specific drugs
- No significant pharmacokinetic interactions with metoclopramide
- Not an inhibitor or inducer of specific CYP enzymes
Contraindications
- Hypersensitivity to the drug or its components
Side Effects
- Headaches
- Constipation
Pregnancy & Lactation
- Pregnancy category 'B'
- Unknown excretion in breast milk
Use in Special Populations
- No dosage adjustment for elderly patients
- Specific dosage for children
- No dosage adjustment for patients with renal and hepatic dysfunction
Overdose Effects
- No known antidote
- Supportive care for management
Therapeutic Class
Anti-emetic drugs
Storage Conditions
- Cool & dry place
- Protected from light