Paloxi 0.25 mg/5 ml (IV Injection)
5 ml ampoule: ৳ 100.30
Medicine Details
Category | Details |
---|---|
Generic | Palonosetron |
Company | Beacon pharmaceuticals plc |
Also available as |
Indications
- Acute and delayed nausea and vomiting
- Uncontrolled nausea and vomiting
- Chemotherapy-induced nausea and vomiting (CINV)
- Radiotherapy-induced nausea and vomiting (RINV)
- Post-operative & Post-discharge nausea and vomiting (PONV & PDNV)
Pharmacology
- 5-HT3 receptor antagonist
- Strong binding affinity for 5-HT3 receptor
- Little or no affinity for other receptors
- Influence on chemotherapeutic agents
- Metabolism and excretion details
Dosage & Administration
- Usual dosage for adults and children
- Specific dosage for different types of nausea and vomiting
Interaction
- Safe administration with various drugs
- No inhibition of antitumor activity
- No significant pharmacokinetic interactions
- Low potential for drug interactions
Contraindications
- Hypersensitivity to the drug or its components
Side Effects
- Headaches
- Constipation
Pregnancy & Lactation
- Pregnancy category 'B'
- Unknown excretion in breast milk
Use in Special Populations
- Use in elderly patients
- Use in children
- Use in patients with impaired renal and hepatic function
Overdose Effects
- No known antidote
- Supportive care for management
Therapeutic Class
- Anti-emetic drugs
Storage Conditions
- Cool and dry storage
- Protection from light