Paloxi 0.25 mg/5 ml (IV Injection)

5 ml ampoule: ৳ 100.30

Medicine Details

Indications

  • Acute and delayed nausea and vomiting
  • Uncontrolled nausea and vomiting
  • Chemotherapy-induced nausea and vomiting (CINV)
  • Radiotherapy-induced nausea and vomiting (RINV)
  • Post-operative & Post-discharge nausea and vomiting (PONV & PDNV)

Pharmacology

  • 5-HT3 receptor antagonist
  • Strong binding affinity for 5-HT3 receptor
  • Little or no affinity for other receptors
  • Influence on chemotherapeutic agents
  • Metabolism and excretion details

Dosage & Administration

  • Usual dosage for adults and children
  • Specific dosage for different types of nausea and vomiting

Interaction

  • Safe administration with various drugs
  • No inhibition of antitumor activity
  • No significant pharmacokinetic interactions
  • Low potential for drug interactions

Contraindications

  • Hypersensitivity to the drug or its components

Side Effects

  • Headaches
  • Constipation

Pregnancy & Lactation

  • Pregnancy category 'B'
  • Unknown excretion in breast milk

Use in Special Populations

  • Use in elderly patients
  • Use in children
  • Use in patients with impaired renal and hepatic function

Overdose Effects

  • No known antidote
  • Supportive care for management

Therapeutic Class

  • Anti-emetic drugs

Storage Conditions

  • Cool and dry storage
  • Protection from light

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