Paloset 0.075 mg/1.5 ml (IV Injection)
1.5 ml ampoule: ৳ 75.22 (1 x 5: ৳ 376.10)
Medicine Details
| Category | Details |
|---|---|
| Generic | Palonosetron |
| Company | Square pharmaceuticals plc |
| Also available as |
Indications
- Acute and delayed nausea and vomiting
- Uncontrolled nausea and vomiting
- Chemotherapy-induced nausea and vomiting (CINV)
- Radiotherapy-induced nausea and vomiting (RINV)
- Post-operative & Post-discharge nausea and vomiting (PONV & PDNV)
Pharmacology
- 5-HT3 receptor antagonist
- Binding affinity
- Chemotherapeutic mechanism
- Neuronal response
- Metabolism process
- Plasma concentration
- Pharmacokinetics
- Protein binding
- Metabolites
- Renal clearance
- Half-life
Dosage & Administration
- Adult tablet dosage
- Adult IV dosage
- Chemotherapy-induced nausea and vomiting dosage
- Radiotherapy-induced nausea and vomiting dosage
- Post-operative nausea and vomiting dosage
- Children dosage
Interaction
- Safe coadministration
- No inhibition of antitumor activity
- No significant pharmacokinetic interactions
- CYP enzyme interactions
Contraindications
- Hypersensitivity
Side Effects
- Headaches
- Constipation
Pregnancy & Lactation
- Pregnancy category
- Excretion in breast milk
Use in Special Populations
- Elderly patients
- Children
- Renal and hepatic function
Overdose Effects
- No known antidote
- Supportive care
Therapeutic Class
- Anti-emetic drugs
Storage Conditions
- Cool & dry place
- Protected from light