Paloxiron 0.075 mg/1.5 ml (IV Injection)

1.5 ml ampoule: ৳ 75.00

Medicine Details

Indications

  • Acute and delayed nausea and vomiting
  • Uncontrolled nausea and vomiting
  • Chemotherapy-induced nausea and vomiting (CINV)
  • Radiotherapy-induced nausea and vomiting (RINV)
  • Post-operative & Post-discharge nausea and vomiting (PONV & PDNV)

Pharmacology

  • 5-HT3 receptor antagonist
  • Binding affinity for 5-HT3 receptor
  • Chemotherapy-induced mechanism of action
  • Radiotherapy-induced mechanism of action
  • Postoperative nausea and vomiting mechanism of action
  • Metabolism and excretion details

Dosage & Administration

  • Usual adult tablet dosage
  • Usual adult IV dosage
  • Chemotherapy-induced nausea and vomiting dosage
  • Radiotherapy-induced nausea and vomiting dosage
  • Post-operative nausea and vomiting dosage
  • Children dosage

Interaction

  • Safe administration with certain drugs
  • No inhibition of antitumor activity
  • No significant pharmacokinetic interactions
  • Inhibition or induction of CYP enzymes

Contraindications

  • Hypersensitivity to the drug or its components

Side Effects

  • Common adverse reactions

Pregnancy & Lactation

  • Pregnancy category
  • Excretion in breast milk

Use in Special Populations

  • Elderly patients dosage recommendation
  • Children dosage recommendation
  • Renal and hepatic dysfunction dosage recommendation

Overdose Effects

  • No known antidote
  • Management with supportive care

Therapeutic Class

  • Anti-emetic drugs

Storage Conditions

  • Storage instructions

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