Panoset 0.25 mg/5 ml (IV Injection)
5 ml ampoule: ৳ 100.00 (1 x 3: ৳ 300.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Palonosetron |
| Company | Opsonin pharma ltd |
| Also available as |
Indications
- Acute and delayed nausea and vomiting
- Uncontrolled nausea and vomiting
- Chemotherapy-induced nausea and vomiting (CINV)
- Radiotherapy-induced nausea and vomiting (RINV)
- Post-operative & Post-discharge nausea and vomiting (PONV & PDNV)
Pharmacology
- 5-HT3 receptor antagonist
- Binding affinity for the 5-HT3 receptor
- Little or no affinity for other receptors
- Mechanism against chemotherapy-induced nausea and vomiting
- Influence on postoperative nausea and vomiting
- Pharmacokinetics characteristics
Dosage and administration
- Usual adult tablet dosage: 0.5 mg daily
- Usual adult IV dosage: 0.075 mg administered over 10 seconds
- Specific dosages for chemotherapy-induced nausea and vomiting
- Specific dosage for radiotherapy-induced nausea and vomiting
- Specific dosage for post-operative nausea and vomiting
- Children dosage: IV dose at 20 mcg/kg body weight
Interaction
- Safe administration with certain medications
- No significant pharmacokinetic interactions with metoclopramide
- Inhibition of antitumor activity
- Low potential for drug interactions
Contraindications
- Hypersensitivity to the drug or any of its components
Side effects
- Headaches
- Constipation
Pregnancy and lactation
- Pregnancy category 'B'
- Unknown excretion in breast milk
Use in special populations
- No dosage adjustment recommended in elderly patients
- Specific dosage for children and patients with impaired renal and hepatic function
Overdose effects
- No known antidote
- Supportive care management
Therapeutic class
- Anti-emetic drugs
Storage conditions
- Store in a cool & dry place
- Protection from light