Anleptic CR 200 mg (Tablet (Controlled Release))

Unit Price: ৳ 6.02 (5 x 10: ৳ 301.00)

Strip Price: ৳ 60.20

Medicine Details

Category	Details
Generic	Carbamazepine
Company	Square pharmaceuticals plc
Also available as	Anleptic 100 mg suspension

Indications

Partial and secondary generalized tonic-clonic seizures
Primary generalized tonic-clonic seizures
Trigeminal neuralgia
Prophylaxis of bipolar disorder

Pharmacology

Carbamazepine depresses activity in the nucleus ventralis of the thalamus, reduces synaptic propagation of excitatory impulses or decreases summation of temporal stimulation leading to neural discharge by limiting influx of Na ions across cell membrane or other unknown mechanisms. It stimulates the release of antidiuretic hormone (ADH) and potentiates its action in promoting reabsorption of water.

Dosage & Administration

Initial and maintenance dosages for different age groups and conditions
Combination therapy with other anticonvulsants
Trigeminal Neuralgia dosage and maintenance

Interaction

Galactorrhoea reported in women on oral contraceptives within the first two months of Anleptic CR treatment. Hepatic enzyme inducers such as Anleptic CR and Phenytoin may interact with Anleptic CR by increasing its metabolism, requiring a dosage increase.

Contraindications

Atrioventricular block
Bone marrow depression
Porphyrias
Allergy to tricyclic antidepressants
Use of monoamine-oxidase inhibitor antidepressant (MAOI) in the last 14 days

Side Effects

Common side effects (dizziness, drowsiness, ataxia, dry mouth, etc.)
Severe adverse reactions in the hemopoietic system, the skin and the cardiovascular system
Increased sun sensitivity
Avoiding sun exposure and use of sunscreen

Pregnancy & Lactation

Pregnancy category D. Carbamazepine and its epoxide metabolite are transferred to breast milk. Decision should be made whether to discontinue nursing or discontinue the drug.

Precautions & Warnings

Caution while performing hazardous activities
Risk of skin reactions
Rarely causing liver problems
Decreasing blood levels of hormonal contraceptives
Caution when stopping the medication suddenly
Caution in mixed seizures, elderly people, history of heart/kidney/liver disease, raised intraocular pressure, previous Anleptic CR therapy interruptions

Therapeutic Class

Primary anti-epileptic drugs

Storage Conditions

Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children