Anleptic 100 mg/5 ml (Oral Suspension)
100 ml bottle: ৳ 300.90
Medicine Details
| Category | Details |
|---|---|
| Generic | Carbamazepine |
| Company | Square pharmaceuticals plc |
| Also available as |
Indications
- partial and secondary generalized tonic-clonic seizures
- Primary generalized tonic-clonic seizures
- Trigeminal neuralgia
- Prophylaxis of bipolar disorder
Pharmacology
Carbamazepine depresses activity in the nucleus ventralis of the thalamus, reduces synaptic propagation of excitatory impulses, decreases summation of temporal stimulation leading to neural discharge, limits influx of Na ions across cell membrane, stimulates the release of antidiuretic hormone (ADH) and potentiates its action in promoting reabsorption of water.
Dosage & Administration
- Dosage varies for adults, children over 12 years of age, children 12-15 years of age, children 6-12 years of age, and children under 6 years of age for different conditions including epilepsy and trigeminal neuralgia
- Combination therapy with other anticonvulsants possible
Interaction
May interact with oral contraceptives and hepatic enzyme inducers like Phenytoin
Contraindications
- Allergy to any ingredients
- Problems with the electrical message pathways in the heart (atrioventricular block)
- History of decreased blood cell production by the bone marrow (bone marrow depression)
- Hereditary blood disorders called porphyrias
- Allergy to tricyclic antidepressants
- Recent use of a monoamine-oxidase inhibitor antidepressant (MAOI)
Side Effects
- Dizziness
- Drowsiness
- Ataxia
- Dry mouth
- Abdominal pain
- Nausea
- Vomiting
- Leucopenia
- Proteinuria
- Bradycardia
- Heart failure
- Hypotension
- Erythematous skin rash
- Aplastic anemia
- Increased sensitivity to the sun
Pregnancy & Lactation
Pregnancy category D. Transferred to breast milk. Decision should be made whether to discontinue nursing or discontinue the drug.
Precautions & Warnings
- May cause dizziness and drowsiness
- May cause skin reactions
- May rarely cause liver problems
- Decreases blood levels of hormonal contraceptives
- Caution needed in various medical conditions
Therapeutic Class
Primary anti-epileptic drugs
Storage Conditions
Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.