Epilep CR 200 mg (Tablet (Controlled Release))
Unit Price: ৳ 4.52 (5 x 10: ৳ 226.00)
Strip Price: ৳ 45.20
Medicine Details
| Category | Details |
|---|---|
| Generic | Carbamazepine |
| Company | Beximco pharmaceuticals ltd |
| Also available as |
Indications
- Partial and secondary generalized tonic-clonic seizures
- Primary generalized tonic-clonic seizures
- Trigeminal neuralgia
- Prophylaxis of bipolar disorder
Pharmacology
- Depresses activity in the nucleus ventralis of the thalamus
- Reduces synaptic propagation of excitatory impulses
- Decreases summation of temporal stimulation leading to neural discharge
- Limits influx of Na ions across cell membrane
- Stimulates the release of antidiuretic hormone (ADH)
- Potentiates the action of ADH in promoting reabsorption of water
Dosage & Administration
- Dosage for adults and children over 12 years of age
- Dosage for children 12-15 years of age
- Dosage for children 6-12 years of age
- Dosage for children under 6 years of age
- Combination therapy with other anticonvulsants
- Dosage for trigeminal neuralgia
- Instructions for taking without regards to meal
Interaction
- Reported interaction with oral contraceptives
- Interaction with hepatic enzyme inducers like Phenytoin
Contraindications
- Allergy to any of its ingredients
- Problems with the electrical message pathways in the heart (atrioventricular block)
- History of decreased blood cell production by the bone marrow (bone marrow depression)
- Hereditary blood disorders called porphyrias
- Allergy to tricyclic antidepressants
- Recent use of monoamine-oxidase inhibitor antidepressants (MAOI)
Side Effects
- Common side effects like dizziness and drowsiness
- Severe adverse reactions observed in the hemopoietic, skin, and cardiovascular system
- Increased sensitivity to the sun
- Possible skin reactions and liver problems
Pregnancy & Lactation
- Pregnancy category D
- Transfer to breast milk
- Consideration for nursing mothers
Precautions & Warnings
- Caution while performing hazardous activities
- Possibility of skin reactions
- Potential for liver problems
- Effect on hormonal contraceptives
- Need for gradual withdrawal under supervision
- Caution for mixed seizures, elderly people, history of heart, kidney, or liver disease, psychotic illness, raised intraocular pressure, and previous therapy interruptions
Therapeutic Class
- Primary anti-epileptic drugs
Storage Conditions
- Storage temperature below 30°C
- Protection from light & moisture
- Keep out of the reach of children