Tegretol CR 200 mg (Tablet (Controlled Release))
Unit Price: ৳ 9.53 (6 x 10: ৳ 571.80)
Strip Price: ৳ 95.30
Medicine Details
| Category | Details |
|---|---|
| Generic | Carbamazepine |
| Company | Novartis bangladesh ltd |
| Also available as |
Indications
- Partial and secondary generalized tonic-clonic seizures
- Primary generalized tonic-clonic seizures
- Trigeminal neuralgia
- Prophylaxis of bipolar disorder
Pharmacology
- Depression of activity in the nucleus ventralis of the thalamus
- Reduction of synaptic propagation of excitatory impulses
- Decrease in summation of temporal stimulation leading to neural discharge
- Limiting influx of Na ions across cell membrane
- Stimulation of the release of antidiuretic hormone (ADH)
- Potentiation of the action of ADH in promoting reabsorption of water
Dosage & Administration
- Initial dosage for adults and children over 12 years of age
- Dosage for children 12-15 years of age
- Dosage for children 6-12 years of age
- Dosage for children under 6 years of age
- Combination therapy guidelines
- Dosage for trigeminal neuralgia
- Maintenance dosage for different age groups
Interaction
- Potential interaction with oral contraceptives
- Interaction with hepatic enzyme inducers like Phenytoin
- Potential need for dosage adjustment
Contraindications
- Allergy to any of the ingredients
- Problems with the electrical message pathways in the heart (atrioventricular block)
- History of decreased blood cell production by the bone marrow (bone marrow depression)
- Hereditary blood disorders called porphyrias
- Allergy to tricyclic antidepressants
- Use of monoamine-oxidase inhibitor antidepressants (MAOIs) in the last 14 days
Side Effects
- Common side effects like dizziness, drowsiness, ataxia, dry mouth, abdominal pain, nausea, and vomiting
- Potential severe adverse reactions in the hemopoietic system, the skin, and the cardiovascular system
- Increased sensitivity to the sun
- Adverse reactions during initial phases of therapy
- Preventive measures for increased sun sensitivity
Pregnancy & Lactation
- Pregnancy category D
- Transfer of carbamazepine and its metabolite to breast milk
- Consideration for potential serious side effects
Precautions & Warnings
- Potential for causing dizziness and drowsiness
- Caution for performing hazardous activities
- Risk of skin reactions
- Rarely causing liver problems
- Impact on blood levels of hormonal contraceptives
- Caution for women requiring contraception
- Instructions for gradual discontinuation of the medicine
- Caution in mixed seizures, elderly people, history of heart/kidney/liver disease, psychotic illness, raised intraocular pressure, history of blood disorders, and previous Tegretol CR therapy
Therapeutic Class
- Primary anti-epileptic drugs
Storage Conditions
- Keep below 30°C temperature
- Away from light & moisture
- Keep out of the reach of children