Clonapin 0.5 mg (Tablet)

Unit Price: ৳ 5.00 (3 x 10: ৳ 150.00)
Strip Price: ৳ 50.00

Medicine Details

Indications

  • Treatment of panic disorder with or without agoraphobia
  • Treatment of Lennox-Gastaut Syndrome (petit mal variant)
  • Akinetic and myoclonic seizures
  • Adjunct in the treatment of the Lennox-Gastaut Syndrome
  • Treatment of absence seizures (petit mal)

Pharmacology

  • Anticonvulsive effects
  • Sedative effects
  • Muscle relaxing effects
  • Anxiolytic effects
  • Enhancement of GABAergic neurotransmission
  • Mediation through positive allosteric modulation

Dosage & Administration

  • Initial dose for adults with seizure disorders
  • Initial dose for adults with panic disorder
  • Pediatric dosage
  • Dosage adjustment increments
  • Maximum recommended daily dose
  • Administration via oral and injection routes

Interaction

  • Lack of alteration in the pharmacokinetics of specific drugs
  • Uninvestigated effect on the metabolism of other drugs

Contraindications

  • Hypersensitivity to benzodiazepines
  • Clinical or biochemical evidence of significant liver disease
  • Acute narrow angle glaucoma

Side Effects

  • CNS depression
  • Drowsiness
  • Ataxia
  • Behavior problems
  • Abnormal eye movements
  • Hallucinations
  • Insomnia
  • Palpitations

Pregnancy & Lactation

  • Potential for producing congenital malformations
  • Evidence of anticonvulsant drugs acting as teratogens
  • Administration only if compelling indication
  • Discontinuation of breastfeeding
  • Risk to the fetus
  • Exacerbation of epilepsy
  • Withdrawal symptoms in newborn infants

Precautions & Warnings

  • Increase in the incidence of generalized tonic-clonic seizures
  • Addition of appropriate anticonvulsants
  • Increased pharmacologic effects in elderly patients
  • No dose adjustment required in renal impairment
  • Reduction in clearance in liver cirrhosis

Use in Special Populations

  • Increased production of saliva and bronchial secretion in infants and small children
  • Greater pharmacologic effects in elderly patients
  • No dose adjustment required in renal impairment
  • Significant differences in plasma protein binding in cirrhotic patients

Overdose Effects

  • Common symptoms: drowsiness, ataxia, dysarthria, nystagmus
  • Rare life-threatening complications
  • Increased frequency of seizures
  • Respiratory depressant effects

Therapeutic Class

  • Adjunct anti-epileptic drugs
  • Benzodiazepine hypnotics

Reconstitution

  • Dilution with water for injection
  • Preparation of injection solution
  • Dilution for intravenous infusion
  • Stability of infusion mixtures

Storage Conditions

  • Dry place away from light and heat
  • Keep out of the reach of children

Chemical Structure

  • Molecular formula: C15H10ClN3O3

Common Questions about Clonapin 0.5 mg Tablet

  • Not used as a sleeping pill
  • Advised duration of use
  • Withdrawal symptoms upon discontinuation
  • Early symptoms of suicidal thoughts and actions
  • Potential for weight gain
  • Effect on memory
  • Harming effects of overdose
  • Interactions with other medications
  • Quick Tips for use

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