Clonapin 2 mg (Tablet)

Unit Price: ৳ 8.00 (3 x 10: ৳ 240.00)
Strip Price: ৳ 80.00

Medicine Details

Indications

  • Treatment of panic disorder
  • Treatment of Lennox-Gastaut Syndrome
  • Treatment of akinetic and myoclonic seizures
  • Adjunct in the treatment of absence seizures
  • Long-term use not systematically studied

Pharmacology

  • Anticonvulsive effects
  • Sedative effects
  • Muscle relaxing effects
  • Anxiolytic effects
  • Enhancement of GABAergic neurotransmission
  • Effect on serotonin
  • Suppression of paroxysmal activity including different types of seizures

Dosage & Administration

  • Oral:
    • Initial dose for adults with seizure disorders
    • Initial dose for adults with panic disorder
    • Initial dose for pediatric patients
    • Maximum recommended daily dose
  • Injection:
    • Dosage for infants and children
    • Dosage for adults
    • Rate and total dose of injection for adults

Interaction

  • No alteration of the pharmacokinetics of certain drugs
  • Effect on the metabolism of other drugs not investigated

Contraindications

  • History of hypersensitivity to benzodiazepines
  • Clinical or biochemical evidence of significant liver disease
  • Contraindicated in acute narrow angle glaucoma

Side Effects

  • CNS depression
  • Drowsiness
  • Ataxia
  • Behavior problems
  • Abnormal eye movements
  • Aphonia
  • Coma
  • Tremor
  • Vertigo
  • Confusion
  • Depression
  • Amnesia
  • Hallucinations
  • Increased libido
  • Insomnia
  • Psychosis
  • Palpitations

Pregnancy & Lactation

  • Potential for producing congenital malformations
  • Use in pregnancy only if potential benefits outweigh risks
  • Administration only if compelling indication
  • Small amounts found in maternal milk
  • Discontinuation of breastfeeding if compelling indication

Precautions & Warnings

  • Possible increase in incidence of generalized tonic-clonic seizures
  • Concomitant use with valproic acid
  • Increased production of saliva and bronchial secretion in infants and small children
  • Greater pharmacologic effects in elderly patients
  • No dose adjustment required in renal impairment
  • Significantly different plasma protein binding in cirrhotic patients

Use in Special Populations

  • Increased pharmacologic effects in elderly patients
  • No dose adjustment required in renal impairment
  • Different plasma protein binding in cirrhotic patients

Overdose Effects

  • Symptoms including drowsiness, ataxia, dysarthria, and nystagmus
  • Not life-threatening if taken alone
  • Monitoring vital signs and supportive measures indicated
  • Activated charcoal for further absorption prevention
  • Consideration of flumazenil for severe CNS depression

Therapeutic Class

  • Adjunct anti-epileptic drugs
  • Benzodiazepine hypnotics

Reconstitution

  • Dilution with water for injection prior to administration
  • Preparation of IV injection solution immediately before use
  • Dilution for infusion in specific ratios and stable for specific durations
  • Usage of IM route only in exceptional cases

Storage Conditions

  • Dry place away from light and heat
  • Keep out of the reach of children

Chemical Structure

  • Molecular Formula: C15H10ClN3O3
  • Chemical Structure Image: https://medex.com.bd/storage/res/g-res-284-clonazepam-chemical-structure-S6GmKrvYS03ZYjOTAtig.svg

Common Questions about Clonapin 2 mg Tablet

  • Not used as a sleeping pill
  • Take as advised by the doctor
  • Common withdrawal symptoms
  • Monitoring for early symptoms of suicidal thoughts and actions
  • Potential weight changes
  • No effect on memory
  • Possible harm with more than recommended doses
  • Precautions and quick tips for use

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