Clonatril 0.5 mg (Tablet)
Unit Price: ৳ 7.00 (5 x 10: ৳ 350.00)
Strip Price: ৳ 70.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Clonazepam |
| Company | Healthcare pharmaceuticals ltd |
| Also available as |
Indications
- Treatment of panic disorder with or without agoraphobia
- Adjunct in the treatment of Lennox-Gastaut Syndrome
- Treatment of akinetic and myoclonic seizures
- Treatment of absence seizures
Pharmacology
- Anticonvulsive effects
- Sedative effects
- Muscle relaxing effects
- Anxiolytic effects
- Enhancement of GABAergic neurotransmission
- Effect on serotonin
- Suppression of paroxysmal activity in seizures
Dosage & Administration
- Initial dose for adults with seizure disorders
- Initial dose for adults with panic disorder
- Dosage for pediatric patients
- Dosage for infants and children
- Dosage for adults in injectable form
Interaction
- Effect on the metabolism of phenytoin, carbamazepine, and phenobarbital
Contraindications
- Hypersensitivity to benzodiazepines
- History of significant liver disease
- Contraindicated in acute narrow angle glaucoma
Side Effects
- CNS depression
- Drowsiness
- Ataxia
- Behavior problems
- Abnormal eye movements
- Confusion
- Hallucinations
- Increased libido
- Insomnia
- Psychosis
- Palpitations
Pregnancy & Lactation
- Potential for producing congenital malformations
- Evidences as a teratogen
- Administration during pregnancy if benefits outweigh risks
- Transfer into maternal milk
- Discontinuation of breastfeeding if using the drug
Precautions & Warnings
- Potential to increase incidence of generalized tonic-clonic seizures
- Increased effects in elderly patients
- No dose adjustment required in renal impairment
- Possible reduced clearance in liver cirrhosis
Use in Special Populations
- Increased production of saliva and bronchial secretion in infants and small children
- Greater pharmacologic effects in elderly patients
- No dose adjustment required in renal impairment
- Possible reduced clearance in liver cirrhosis
Overdose Effects
- Symptoms include drowsiness, ataxia, dysarthria, nystagmus
- Seldom life-threatening when taken alone
- Potential for areflexia, apnoea, hypotension, cardiorespiratory depression and coma
- Monitoring of vital signs and supportive measures
Therapeutic Class
- Adjunct anti-epileptic drugs
- Benzodiazepine hypnotics
Reconstitution
- Preparation for slow intravenous injection
- Dilution for intravenous infusion
- Limitations of intramuscular injection
Storage Conditions
- Storage in a dry place away from light and heat
- Keep out of reach of children
Chemical Structure
- Molecular Formula: C15H10ClN3O3
Common Questions
- Use as a sleeping pill
- Long-term use
- Withdrawal symptoms
- Early symptoms of suicidal thoughts and actions
- Effect on memory
- Harmful effects of overdose
- Combination with other medications