Clonatril 2 mg (Tablet)
Unit Price: ৳ 11.00 (3 x 10: ৳ 330.00)
Strip Price: ৳ 110.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Clonazepam |
| Company | Healthcare pharmaceuticals ltd |
| Also available as |
Indications
- Treatment of panic disorder with or without agoraphobia
- Treatment of Lennox-Gastaut Syndrome and related seizures
- Use alone or as an adjunct in seizure treatment
- Long-term use not systematically studied
Pharmacology
- Anticonvulsive effects
- Sedative effects
- Muscle relaxing effects
- Anxiolytic effects
- Enhancement of GABAergic neurotransmission
- Positive allosteric modulation of GABA receptor
Dosage & Administration
- Initial dose for adults with seizure disorders
- Initial dose for adults with panic disorder
- Dosage increment guidelines
- Maximum recommended daily dose for adults
- Pediatric dosage instructions
- Infants and children dosage guidelines
Interaction
- Lack of alteration to phenytoin, carbamazepine, or phenobarbital pharmacokinetics
- Uninvestigated effect on the metabolism of other drugs
Contraindications
- Hypersensitivity to benzodiazepines
- History of clinical or biochemical evidence of significant liver disease
- Contraindicated in acute narrow angle glaucoma
Side Effects
- CNS depression
- Drowsiness
- Ataxia
- Behavior problems
- Abnormal eye movements
- Tremor
- Vertigo
- Depression
- Hallucinations
- Insomnia
- Palpitations
Pregnancy & Lactation
- Potential for producing congenital malformations
- Evidence of anticonvulsant drugs acting as teratogens
- Administration only if potential benefits outweigh the risk to the fetus
- Compelling indication for administration during pregnancy
Precautions & Warnings
- Increased incidence of generalized tonic-clonic seizures in certain patient populations
- Concomitant use producing absence status
- Special precautions needed for infants and small children
- Greater pharmacologic effects in elderly patients
Use in Special Populations
- Increased saliva and bronchial secretion in infants and small children
- Greater pharmacologic effects in elderly patients
- No dose adjustment required in renal impairment
- Possible reduced clearance in liver cirrhosis
Overdose Effects
- Symptoms including drowsiness, ataxia, dysarthria, nystagmus
- Life-threatening effects when combined with other CNS depressants
- Symptomatic treatment for cardiorespiratory effects
Therapeutic Class
- Adjunct anti-epileptic drugs
- Benzodiazepine hypnotics
Reconstitution
- Guidelines for slow intravenous injection
- Guidelines for intravenous infusion
- Guidelines for intramuscular injection
Storage Conditions
- Dry place away from light and heat
- Keep out of the reach of children
Chemical Structure
- Molecular Formula: C15H10ClN3O3
- Image showing chemical structure
Common Questions
- Medication usage as a sleeping pill
- Usage duration as per doctor's advice
- Withdrawal symptoms after discontinuation
- Early symptoms of suicidal thoughts/actions
- Impact on weight and memory
- Harmful effects of overdose or combination with other medications
- Cautionary tips for usage