Clonium 2 mg (Tablet)
Unit Price: ৳ 14.00 (5 x 10: ৳ 700.00)
Strip Price: ৳ 140.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Clonazepam |
| Company | Aci limited |
| Also available as |
Indications
- Treatment of panic disorder with or without agoraphobia
- Treatment of Lennox-Gastaut Syndrome (petit mal variant)
- Adjunct in the treatment of akinetic and myoclonic seizures
- Treatment of absence seizures (petit mal) in patients who have failed to respond to succinimides
Pharmacology
- Anticonvulsive effects
- Sedative effects
- Muscle relaxing effects
- Anxiolytic effects
- Enhancement of GABAergic neurotransmission
- Suppression of paroxysmal activity
Dosage & Administration
- Initial dose for adults with seizure disorders: not to exceed 1.5 mg/day divided into three doses
- Initial dose for adults with panic disorder: 0.25 mg given in two divided doses
- Pediatric dose for infants and children: 0.01-0.03 mg/kg/day divided into two or three doses
- Maximum recommended daily dose: 20 mg
Interaction
- No alteration of the pharmacokinetics of phenytoin, carbamazepine, or phenobarbital observed
- Effect on the metabolism of other drugs has not been investigated
Contraindications
- History of hypersensitivity to benzodiazepines
- Clinical or biochemical evidence of significant liver disease
- Acute narrow angle glaucoma
Side Effects
- CNS depression
- Drowsiness
- Ataxia
- Behavior problems
- Abnormal eye movements
- Aphonia
- Coma
- Tremor
- Vertigo
- Confusion
- Depression
- Amnesia
- Hallucinations
- Increased libido
- Insomnia
- Psychosis
- Palpitations
Pregnancy & Lactation
- Potential teratogenicity
- Administration during pregnancy only if compelling indication
- Administration during labor can cause irregularities in the heartbeat of the unborn child
Precautions & Warnings
- May increase the incidence of generalized tonic-clonic seizures in certain patients
Use in Special Populations
- Caution required in pediatric use due to increased salivation and bronchial secretion
- Benzodiazepine pharmacologic effects appear to be greater in elderly patients
- Renal impairment does not affect the pharmacokinetics
Overdose Effects
- Symptoms: drowsiness, ataxia, dysarthria, nystagmus
- May lead to areflexia, apnoea, hypotension, cardiorespiratory depression, and coma
- Increased frequency of seizures at supratherapeutic plasma concentrations
Therapeutic Class
- Adjunct anti-epileptic drugs
- Benzodiazepine hypnotics
Reconstitution
- Instructions for slow intravenous injection
- Instructions for intravenous infusion
- Instructions for intramuscular injection
Storage Conditions
- Keep in a dry place away from light and heat
- Keep out of the reach of children
Chemical Structure
- Molecular Formula: C15H10ClN3O3
Common Questions
- Not used as a sleeping pill
- Need to take as advised by the doctor
- Common withdrawal symptoms include difficulty in sleeping, changes in mood, and increased sweating
- Early symptoms of suicidal thoughts and actions should be monitored
- May cause weight gain and weight loss
- Does not affect memory
- Overdose effects include sleepiness, change in speech, confusion, abnormalities in eye movement