Denixil 0.5 mg (Tablet)
Unit Price: ৳ 6.50 (8 x 10: ৳ 520.00)
Strip Price: ৳ 65.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Clonazepam |
| Company | Renata limited |
| Also available as |
Indications
- Treatment of panic disorder with or without agoraphobia
- Treatment of Lennox-Gastaut Syndrome (petit mal variant)
- Treatment of akinetic and myoclonic seizures
- Adjunct in the treatment of absence seizures (petit mal)
- Long-term use effectiveness
- Systematic study in controlled clinical trials
Pharmacology
- Anticonvulsive effects
- Sedative effects
- Muscle relaxing effects
- Anxiolytic effects
- GABAergic neurotransmission enhancement
- Serotonin impact
- Suppresses paroxysmal activity in seizures
- EEG abnormalities suppression
Dosage & Administration
- Initial dose for adults with seizure disorders
- Maximum recommended daily dose for adults
- Initial dose for adults with panic disorder
- Pediatric patients initial dose
- Injection dosage for infants, children, and adults
Interaction
- Effect on the metabolism of phenytoin, carbamazepine, and phenobarbital
- Impact on the metabolism of other drugs
Contraindications
- History of hypersensitivity to benzodiazepines
- Clinical or biochemical evidence of significant liver disease
- Open angle glaucoma with appropriate therapy
- Acute narrow angle glaucoma
Side Effects
- CNS depression
- Drowsiness
- Ataxia
- Behavior problems
- Abnormal eye movements
- Aphonia
- Tremor
- Vertigo
- Confusion
- Depression
- Amnesia
- Hallucinations
- Hysteria
- Increased libido
- Insomnia
- Psychosis
- Palpitations
Pregnancy & Lactation
- Potential to produce congenital malformations
- Anticonvulsant drugs as teratogens
- Administration during pregnancy
- Administration during the last trimester
- Impact on the heartbeat of the unborn child
- Impact on the neonate
- Passage into maternal milk
Precautions & Warnings
- Increase in generalized tonic-clonic seizures
- Concomitant use of valproic acid
- Pediatric use impact
- Geriatric use impact
- Renal impairment impact
- Hepatic impairment impact
Use in Special Populations
- Increased production of saliva and bronchial secretion in infants and small children
- Greater benzodiazepine pharmacologic effects in elderly patients
- Impact of renal impairment on pharmacokinetics
- Influence of hepatic impairment on pharmacokinetics
Overdose Effects
- Drowsiness
- Ataxia
- Dysarthria
- Nystagmus
- Coma
- Respiratory depression
- Increased frequency of seizures
- Respiratory depressant effects with respiratory disease
- Enhanced effects with other CNS depressants
- Treatment and patient monitoring
Therapeutic Class
- Adjunct anti-epileptic drugs
- Benzodiazepine hypnotics
Reconstitution
- Dilution with water for injection
- Preparation of IV injection solution
- Preparation of IV infusion solution
- Preparation of IM route solution
- Stability of infusion mixtures
- Avoidance of preparation using sodium bicarbonate solution
Storage Conditions
- Dry place away from light and heat
- Keep out of the reach of children
Chemical Structure
- Molecular Formula: C15H10ClN3O3
- Chemical Structure Image
Common Questions about Denixil 0.5 mg Tablet
- Usage as a sleeping pill
- Long-term usage recommendations
- Withdrawal symptoms
- Early symptoms of suicidal thoughts
- Impact on weight
- Effect on memory
- Harmfulness of exceeding recommended doses
- Drug interactions with zolpidem and quetiapine
- Quick Tips