Denixil 2 mg (Tablet)
Unit Price: ৳ 13.00 (3 x 10: ৳ 390.00)
Strip Price: ৳ 130.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Clonazepam |
| Company | Renata limited |
| Also available as |
Indications
- Treatment of panic disorder
- Treatment of Lennox-Gastaut Syndrome
- Treatment of akinetic and myoclonic seizures
- Treatment of absence seizures (petit mal)
- Long-term use efficacy not systematically studied
Pharmacology
- Exhibits anticonvulsive effects
- Exhibits sedative effects
- Exhibits muscle relaxing effects
- Enhances GABAergic neurotransmission
- Animal data showing an effect on serotonin
- Suppresses various types of paroxysmal activity
Dosage & Administration
- Initial dose for adults with seizure disorders
- Initial dose for adults with panic disorder
- Initial dose for pediatric patients
- Dosage increment guidelines
- Maximum recommended daily dose
Interaction
- Does not alter the pharmacokinetics of phenytoin, carbamazepine, or phenobarbital
- Effect on the metabolism of other drugs not investigated
Contraindications
- Hypersensitivity to benzodiazepines
- Clinical or biochemical evidence of significant liver disease
- Contradicted in acute narrow angle glaucoma
Side Effects
- CNS depression
- Drowsiness
- Ataxia
- Behavior problems
- Abnormal eye movements
- Tremor
- Confusion
- Depression
- Increased libido
- Insomnia
- Psychosis
- Palpitations
Pregnancy & Lactation
- Potential to produce congenital malformations
- Evidence of anticonvulsant drugs acting as teratogens
- Administration during pregnancy only if benefits outweigh risks
- Potential impact on the unborn child
Precautions & Warnings
- Potential increase in incidence of seizures
- Concomitant use with valproic acid
- Increased production of saliva and bronchial secretion in infants
- Greater pharmacologic effects in elderly patients
- No dose adjustment required in patients with renal impairment
- Influence of hepatic impairment on pharmacokinetics
Use in Special Populations
- Influence on different age groups - pediatric and geriatric
- No dose adjustment required in renal impairment
- Potential impact of hepatic impairment on pharmacokinetics
Overdose Effects
- Common symptoms of overdose
- Symptomatic treatment for cardiorespiratory effects or CNS effects
- Use of flumazenil, a benzodiazepine antagonist
- Monitoring required after effects of flumazenil wear off
- Caution in the presence of drugs that reduce seizure threshold
Therapeutic Class
- Adjunct anti-epileptic drugs
- Benzodiazepine hypnotics
Reconstitution
- Preparation for slow intravenous injection
- Preparation for intravenous infusion
- Preparation for intramuscular injection
- Stability of diluting media
- Use of infusion bags for infusing
Storage Conditions
- Dry place away from light and heat
- Keep out of the reach of children
Chemical Structure
- Molecular formula
- Chemical structure
Common Questions
- Usage as a sleeping pill
- Duration of usage
- Withdrawal symptoms
- Early symptoms of suicidal thoughts and actions
- Impact on weight
- Effect on memory
- Harmful effects of exceeding recommended doses
- Interaction with other medications
- Quick tips for usage