Esypan 2 mg (Tablet)

Unit Price: ৳ 4.01 (5 x 10: ৳ 200.50)
Strip Price: ৳ 40.10

Medicine Details

Category Details
Generic Clonazepam
Company Silva pharmaceuticals ltd
Also available as

Indications

  • Treatment of panic disorder
  • Treatment of Lennox-Gastaut Syndrome
  • Treatment of akinetic seizures
  • Treatment of myoclonic seizures
  • Adjunct in the treatment of petit mal seizures
  • Long-term use evaluation

Pharmacology

  • Exhibits anticonvulsive effects
  • Exhibits sedative effects
  • Exhibits muscle relaxing effects
  • Exhibits anxiolytic effects
  • Enhances GABAergic neurotransmission
  • Modulates GABA receptor affinity
  • Suppresses paroxysmal activity
  • Mediates through serotonin

Dosage & Administration

  • Initial dose for adults with seizure disorders
  • Initial dose for adults with panic disorder
  • Initial dose for pediatric patients
  • Administration for infants and children
  • Administration for adults

Interaction

  • Alteration of pharmacokinetics
  • Effect on the metabolism of other drugs

Contraindications

  • Hypersensitivity to benzodiazepines
  • Clinical or biochemical evidence of significant liver disease
  • Open angle glaucoma
  • Acute narrow angle glaucoma

Side Effects

  • CNS depression
  • Drowsiness
  • Ataxia
  • Behavior problems
  • Abnormal eye movements
  • Aphonia
  • Coma
  • Tremor
  • Vertigo
  • Increased libido
  • Insomnia
  • Psychosis
  • Palpitations

Pregnancy & Lactation

  • Potential for producing congenital malformations
  • Evidence of acting as teratogens
  • Administration during pregnancy with compelling indication only
  • Administration during pregnancy may cause irregularities in the heartbeat of the unborn child
  • Active ingredient passing into maternal milk
  • Discontinuation of breastfeeding if compelling indication

Precautions & Warnings

  • Increased incidence of generalized tonic-clonic seizures
  • Concomitant use with valproic acid
  • Increased pharmacologic effects in elderly patients
  • No dose adjustment for renal impairment
  • Influence of hepatic impairment on pharmacokinetics

Use in Special Populations

  • Increased production of saliva in infants and small children
  • Benzodiazepine effects appear to be greater in elderly patients
  • No dose adjustment required for renal impairment
  • Significant difference in plasma protein binding in cirrhotic patients

Overdose Effects

  • Symptoms of overdose
  • Monitoring vital signs
  • Institute supportive measures
  • Preventing further absorption
  • Consideration of flumazenil use with caution

Therapeutic Class

  • Adjunct anti-epileptic drugs
  • Benzodiazepine hypnotics

Reconstitution

  • Preparation of injection solution
  • Administration of slow intravenous injection
  • Dilution for intravenous infusion
  • Stability and infusion guidelines
  • Intramuscular injection - exceptional cases

Storage Conditions

  • Dry place away from light and heat
  • Keep out of the reach of children

Chemical Structure

  • Molecular Formula : C15H10ClN3O3
  • Chemical Structure Image

Common Questions

  • Use as a sleeping pill
  • Long-term usage
  • Withdrawal symptoms
  • Early symptoms of suicidal thoughts and actions
  • Effect on weight
  • Effect on memory
  • Harmful effects of overdose
  • Combination with other drugs
  • Quick Tips

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