Pase 0.5 mg (Tablet)
Unit Price: ৳ 6.50 (7 x 15: ৳ 682.50)
Strip Price: ৳ 97.50
Medicine Details
| Category | Details |
|---|---|
| Generic | Clonazepam |
| Company | Opsonin pharma ltd |
| Also available as |
Indications
- Treatment of panic disorder with or without agoraphobia
- Adjunct in the treatment of Lennox-Gastaut Syndrome
- Treatment of akinetic and myoclonic seizures
Pharmacology
- Exhibits anticonvulsive, sedative, muscle relaxing, and anxiolytic effects
- Enhances GABAergic neurotransmission
- Suppresses different paroxysmal activities in seizures
- Shows effect on serotonin in animal data
Dosage & Administration
- Initial and maintenance doses for adults with seizure disorders
- Initial and target doses for adults with panic disorder
- Initial dose for pediatric patients
- Dosage for infants and children
- Dosage for injection in infants, children, and adults
Interaction
- No alteration in the pharmacokinetics of phenytoin, carbamazepine, or phenobarbital
- Effect on the metabolism of other drugs not investigated
Contraindications
- History of hypersensitivity to benzodiazepines
- Clinical or biochemical evidence of significant liver disease
- Not recommended in acute narrow angle glaucoma
Side Effects
- CNS depression, drowsiness, ataxia, behavior problems, abnormal eye movements, aphonia, coma, tremor, vertigo, confusion, depression, amnesia, hallucinations, increased libido, insomnia, psychosis, palpitations
Pregnancy & Lactation
- Potential to cause congenital malformations
- Use only if benefits outweigh risks during pregnancy
- Cautious administration during breastfeeding
- Possibility of withdrawal symptoms in newborns
Precautions & Warnings
- May increase incidence of generalized tonic-clonic seizures in certain patients
- Concomitant use with valproic acid may produce absence status
Use in Special Populations
- Increased production of saliva and bronchial secretion in infants and small children
- Benzodiazepine effects appear to be greater in elderly patients
- No dose adjustment required in renal impairment
- Influence on plasma protein binding in cirrhotic patients
Overdose Effects
- Common symptoms include drowsiness, ataxia, dysarthria, nystagmus
- Potential effects on vital signs, cardiorespiratory and CNS
- Use of flumazenil as a benzodiazepine antagonist under monitored conditions
Therapeutic Class
- Adjunct anti-epileptic drugs
- Benzodiazepine hypnotics
Reconstitution
- Guidelines for slow intravenous injection, intravenous infusion, and intramuscular injection
Storage Conditions
- Keep in a dry place away from light and heat
- Keep out of the reach of children
Chemical Structure
- Molecular Formula: C15H10ClN3O3
- Chemical Structure Image
Common Questions about Pase 0.5 mg Tablet
- Information about usage as a sleeping pill
- Withdrawal symptoms on stopping
- Monitoring for early symptoms of suicidal thoughts and actions
- Effect on memory
- Likelihood of weight gain
- Potential harm if exceeding recommended doses
- Possible drug interactions