Rivotril 2 mg (Tablet)
Unit Price: ৳ 14.00 (6 x 10: ৳ 840.00)
Strip Price: ৳ 140.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Clonazepam |
| Company | Radiant pharmaceuticals ltd |
| Also available as |
Indications
- Treatment of panic disorder
- Treatment of Lennox-Gastaut Syndrome
- Treatment of seizure disorders
Pharmacology
- Exhibits anticonvulsive effects
- Has sedative and anxiolytic effects
- Enhances GABAergic neurotransmission
- Suppresses multiple types of paroxysmal activity
Dosage & Administration
- Initial dose for adults with seizure disorders should not exceed 1.5 mg/day
- Initial dose for adults with panic disorder is 0.25 mg
- Dosage may be increased in increments of 0.5 to 1 mg every 3 days
Interaction
- Does not alter the pharmacokinetics of phenytoin, carbamazepine, or phenobarbital
Contraindications
- Hypersensitivity to benzodiazepines
- Clinical or biochemical evidence of significant liver disease
- Acute narrow angle glaucoma
Side Effects
- Drowsiness
- Ataxia
- Behavior problems
- Abnormal eye movements
- Hallucinations
- Insomnia
- Increased libido
Pregnancy & Lactation
- Potential for producing congenital malformations
- Anticonvulsant drugs act as teratogens
- Breastfeeding should be discontinued if there is a compelling indication for Clonazepam
Precautions & Warnings
- May increase the incidence of generalized tonic-clonic seizures in patients with multiple seizure disorders
- Concomitant use with valproic acid may produce absence status
Use in Special Populations
- May cause increased production of saliva and bronchial secretion in infants and small children
- Benzodiazepine effects appear to be greater in elderly patients
- Renal impairment does not affect pharmacokinetics
Overdose Effects
- Can cause drowsiness, ataxia, dysarthria, and nystagmus
- May lead to areflexia, apnoea, hypotension, and coma
- Benzodiazepines increase the effects of other central nervous system depressants, including alcohol
Therapeutic Class
- Adjunct anti-epileptic drugs
- Benzodiazepine hypnotics
Reconstitution
- Requires dilution with water for injection prior to administration
- Can be diluted for infusion in specific ratios with various diluting media
Storage Conditions
- Keep in a dry place away from light and heat
- Keep out of the reach of children
Chemical Structure
- Molecular Formula: C15H10ClN3O3
- Chemical Structure: Image of Clonazepam chemical structure
Common Questions about Rivotril 2 mg Tablet
- Not used as a sleeping pill
- Need to take it as long as advised by the doctor
- Withdrawal symptoms may include difficulty in sleeping, changes in mood, and increased sweating
- Early symptoms of suicidal thoughts and actions should be monitored
- May cause weight gain and weight loss in some cases
- Does not affect memory, but may affect the ability to recall the recent past
- Overdose can cause sleepiness, changes in speech, confusion, and abnormalities in eye movement
- Combination with other medications should be avoided
- Addiction/habit-forming potential is very high, should be taken as per the dose and duration advised by the doctor
- May cause dizziness, avoidance of alcohol consumption
- Doctor should be informed in case of pregnancy, planning to conceive, or breastfeeding
- Sudden discontinuation should be avoided without consulting the doctor