Clonaben 0.5 mg (Tablet)

Unit Price: ৳ 8.00 (5 x 10: ৳ 400.00)
Strip Price: ৳ 80.00

Medicine Details

Indications

  • Treatment of panic disorder
  • Treatment of Lennox-Gastaut Syndrome
  • Treatment of akinetic and myoclonic seizures
  • Use as an adjunct in the treatment of petit mal seizures
  • Long-term use effectiveness
  • Evaluation of long-term usefulness

Pharmacology

  • Anticonvulsive effects
  • Sedative effects
  • Muscle relaxing effects
  • Anxiolytic effects
  • Enhancement of GABAergic neurotransmission
  • Modulation of GABA receptor affinity
  • Suppression of paroxysmal activity
  • Effect on serotonin
  • EEG abnormalities suppression
  • Beneficial effects in generalized and focal epilepsies

Dosage & Administration

  • Initial dose for adults with seizure disorders
  • Maximum recommended daily dose for adults
  • Initial dose for adults with panic disorder
  • Initial dose for pediatric patients
  • Dosage adjustment based on response
  • Dosage increment intervals
  • Administration for infants and children
  • Slow IV injection for infants, children, and adults
  • IV infusion for infants, children, and adults
  • Administration rate limits and total dose cautions

Interaction

  • Effect on the metabolism of phenytoin, carbamazepine, and phenobarbital
  • Lack of investigation into the metabolism of other drugs

Contraindications

  • Hypersensitivity to benzodiazepines
  • Clinical or biochemical evidence of significant liver disease
  • Open angle glaucoma with appropriate therapy
  • Acute narrow angle glaucoma

Side Effects

  • CNS depression
  • Drowsiness incidence
  • Ataxia incidence
  • Behavior problems occurrence
  • Abnormal eye movements
  • Aphonia occurrence
  • Coma incidence
  • Tremor occurrence
  • Vertigo occurrence
  • Confusion occurrence
  • Depression occurrence
  • Amnesia occurrence
  • Hallucinations
  • Hysteria occurrence
  • Increased libido occurrence
  • Insomnia occurrence
  • Psychosis occurrence
  • Palpitations

Pregnancy & Lactation

  • Potential for producing congenital malformations
  • Epidemiological evidence of teratogenic activity
  • Difficulty in determining responsible agents for defects
  • Cautionary administration during pregnancy
  • Effects of high doses in the last trimester
  • Effects on the newborn
  • Factors contributing to birth defects
  • Advice on breastfeeding

Precautions & Warnings

  • Increased incidence of generalized tonic-clonic seizures
  • Concomitant use with valproic acid
  • Side effects consideration in infants and small children
  • Greater pharmacologic effects in geriatric patients
  • Impact of renal impairment on pharmacokinetics
  • Impact of hepatic impairment on plasma protein binding

Use in Special Populations

  • Increased production of saliva and bronchial secretion in infants and small children
  • Greater pharmacologic effects in geriatric patients
  • Unaffected pharmacokinetics in renal impairment
  • Differences in plasma protein binding in cirrhotic patients

Overdose Effects

  • Symptoms of benzodiazepine overdose
  • Life-threatening effects when taken alone
  • Respiratory depressant effects in patients with respiratory disease
  • Interaction effects with other CNS depressants
  • Monitoring of vital signs and supportive measures
  • Use of activated charcoal and gastric lavage
  • Use of flumazenil as a benzodiazepine antagonist
  • Potential cyclical coma in elderly patients

Therapeutic Class

  • Adjunct anti-epileptic drugs
  • Benzodiazepine hypnotics

Reconstitution

  • Preparation of IV injection solution
  • Dilution for intravenous infusion
  • Selection of diluting media
  • Stability and infusion duration
  • Cautions for PVC infusion bags

Storage Conditions

  • Dry place storage
  • Protection from light and heat
  • Keep out of reach of children

Chemical Structure

  • Molecular formula
  • Chemical structure image

Common Questions about Clonaben 0.5 mg Tablet

  • Use as a sleeping pill
  • Long-term usage advice
  • Withdrawal symptoms upon discontinuation
  • Early symptoms of suicidal thoughts and actions
  • Effects on weight gain or loss
  • Impact on memory
  • Harmful effects of excess doses
  • Concurrent use with other medications
  • Quick tips for safe use

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