Clonil 0.5 mg (Tablet)
Unit Price: ৳ 7.00 (5 x 10: ৳ 350.00)
Strip Price: ৳ 70.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Clonazepam |
| Company | Jenphar bangladesh ltd |
| Also available as |
Indications
- Treatment of panic disorder with or without agoraphobia
- Treatment of Lennox-Gastaut Syndrome (petit mal variant)
- Adjunct in the treatment of akinetic and myoclonic seizures
- Treatment of patients with absence seizures (petit mal) who have failed to respond to succinimides
Pharmacology
- Anticonvulsive effects
- Sedative effects
- Muscle relaxing effects
- Anxiolytic effects
- Enhancement of GABAergic neurotransmission
- Positive allosteric modulation of GABA receptor
- Effect on serotonin levels
- Suppression of paroxysmal activity including spike and wave discharge in absences seizures
Dosage & Administration
- Initial dose for adults with seizure disorders
- Initial dose for adults with panic disorder
- Initial dose for pediatric patients
- Dosing increment guidelines
- Maximum recommended daily dose
- Administration via oral route
- Administration via injection
- Slow IV injection guidelines
- IV infusion guidelines
Interaction
- Effect on the metabolism of phenytoin, carbamazepine, or phenobarbital
- Lack of investigation on the effect on the metabolism of other drugs
Contraindications
- History of hypersensitivity to benzodiazepines
- Clinical or biochemical evidence of significant liver disease
- Presence of open angle glaucoma, contraindicated in acute narrow angle glaucoma
Side Effects
- CNS depression
- Drowsiness
- Ataxia
- Behavior problems
- Abnormal eye movements
- Aphonia
- Tremor
- Vertigo
- Depression
- Amnesia
- Hallucinations
- Hysteria
- Increased libido
- Insomnia
- Psychosis
- Palpitations
Pregnancy & Lactation
- Potential to produce congenital malformations
- Epidemiological evidence on teratogenicity of anticonvulsant drugs
- Administration during pregnancy based on compelling indication
- Risk of irregularities in the heartbeat of the unborn child
- Risk of adverse effects on the neonate during high-dose administration
- Passage into maternal milk
- Compelling indication for administration to breastfeeding mothers
Precautions & Warnings
- Potential to increase the incidence or onset of generalized tonic-clonic seizures in certain patient populations
- Potential interaction with valproic acid leading to absence status
Use in Special Populations
- Increased production of saliva and bronchial secretion in infants and small children
- Greater pharmacologic effects in elderly patients
- Unaffected pharmacokinetics in patients with renal impairment
- Variations in plasma protein binding in cirrhotic patients
Overdose Effects
- Common symptoms
- Potential cardiorespiratory effects
- Recommendations for monitoring and symptomatic treatment
- Prevention of further absorption using activated charcoal
- Consideration of flumazenil use for severe CNS depression
Therapeutic Class
- Adjunct anti-epileptic drugs
- Benzodiazepine hypnotics
Reconstitution
- Guidelines for slow intravenous injection
- Guidelines for intravenous infusion
- Guidelines for intramuscular injection
Storage Conditions
- Requirement for dry place away from light and heat
- Protection from children
Chemical Structure
- Molecular formula
- Chemical structure visualization
Common Questions about Clonil 0.5 mg Tablet
- Usage as a sleeping pill
- Long-term usage guidelines
- Withdrawal symptoms upon discontinuation
- Early symptoms of suicidal thoughts and actions
- Effect on weight
- Effect on memory
- Harmful effects of exceeding recommended doses
- Potential interactions with other medications
- Quick tips for usage and precautions