Xioclon 0.5 mg (Tablet)

Unit Price: ৳ 6.00 (5 x 10: ৳ 300.00)
Strip Price: ৳ 60.00

Medicine Details

Title

Xioclon 0.5 mg Tablet

Categories

  • Medicine
  • Anti-epileptic
  • Benzodiazepine hypnotics

Description

Xioclon 0.5 mg Tablet is indicated for the treatment of panic disorder, with or without agoraphobia, and as an adjunct in the treatment of the Lennox-Gastaut Syndrome, akinetic and myoclonic seizures. It exhibits anticonvulsive, sedative, muscle relaxing, and anxiolytic effects.

Indication

  • Treatment of panic disorder
  • Adjunct in the treatment of Lennox-Gastaut Syndrome
  • Treatment of seizures

Pharmacology

  • Enhancement of GABAergic neurotransmission
  • Effect on serotonin
  • Suppression of paroxysmal activity

Dosage and administration

  • Initial dose for adults with seizure disorder not to exceed 1.5 mg/day
  • Initial dose for adults with panic disorder is 0.25 mg
  • Dosage for pediatric patients

Interaction

  • No known alteration of the pharmacokinetics of certain drugs

Contraindications

  • History of hypersensitivity to benzodiazepines
  • Clinical or biochemical evidence of significant liver disease
  • Contradicted in acute narrow angle glaucoma

Side effects

  • CNS depression
  • Drowsiness
  • Ataxia
  • Behavior problems
  • Abnormal eye movements
  • Coma
  • Tremor
  • Confusion
  • Palpitations

Pregnancy and lactation

  • Possibility of producing congenital malformations
  • Recommendation to administer only if benefits outweigh the risks
  • Passage into maternal milk
  • Discontinuation of breastfeeding if compelling indication

Precautions and warnings

  • Potential to increase the incidence of certain seizures
  • Concomitant use with valproic acid may produce absence status

Special populations use

  • Increased production of saliva and bronchial secretion in infants and small children
  • Benzodiazepine pharmacologic effects greater in elderly patients
  • No dose adjustment in renal impairment
  • Potential impact of hepatic impairment on pharmacokinetics

Overdose effects

  • Symptoms include drowsiness, ataxia, dysarthria, and nystagmus
  • Severe CNS depression may require the use of flumazenil

Therapeutic class

  • Adjunct anti-epileptic drugs
  • Benzodiazepine hypnotics

Reconstitution

  • Guidelines for slow intravenous injection
  • Guidelines for intravenous infusion in specific dilution ratios and stable mixtures

Storage conditions

  • Keep in a dry place away from light and heat
  • Keep out of the reach of children

Chemical structure

  • Molecular Formula: C15H10ClN3O3
  • Chemical Structure Image

Commonly asked questions

  • Information on use as a sleeping pill
  • Recommendation on duration of use
  • Early symptoms of withdrawal
  • Effects on weight and memory
  • Information on drug interactions
  • Quick Tips for usage

Compound summary

Information on molecular formula and chemical structure

Mode of action

Information on pharmacological properties and effects

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