Gabantin 100 mg (Tablet)

Unit Price: ৳ 6.02 (5 x 10: ৳ 301.00)
Strip Price: ৳ 60.20

Medicine Details

Category Details
Generic Gabapentin
Company Sun pharmaceutical bangladesh ltd
Also available as

Indications

  • Neuropathic Pain
  • Adjunctive therapy in partial seizure and secondary generalized seizure

Pharmacology

  • Structural analog of gamma-amino-butyric-acid (GABA)
  • Binds with the alpha-2-delta subunit of voltage gated L-type Calcium channel
  • Inhibits branched chain amino acid transferase
  • Inhibits neurotransmitter release of excitatory amino acid

Dosage

  • 300 mg single dose initiated on Day-1
  • 300 mg twice on Day-2
  • 300 mg thrice on Day-3
  • Daily dose of 1800 mg for Neuropathic Pain
  • 900 to 1800 mg/day for Epilepsy in patients over 12 years of age
  • Starting dose of 300 mg three times a day for Epilepsy in patients over 12 years of age
  • Starting dose ranging from 10-15 mg/kg/day for Paediatric patients age 3-12 year

Administration

Oral administration with or without food

Interaction

  • Reduction in bioavailability by up to 20% with antacids
  • Possible alteration in renal excretion with Cimetidine
  • No interaction with other anti-epileptic drugs or with oral contraceptive preparations

Contraindications

Known hypersensitivity to the drug

Side Effects

  • Fatigue
  • Dizziness
  • Ataxia
  • Weight gain
  • Peripheral edema
  • Dry mouth
  • Somnolence

Pregnancy & Lactation

Pregnancy category C, potential risk to the fetus, potential risk to the baby during lactation

Precautions & Warnings

Instruction to take as prescribed, caution while driving or operating machinery, especially for first-time users

Use in Special Populations

Dose reduction for renal impaired patients

Therapeutic Class

Adjunct anti-epileptic drugs

Storage Conditions

Store below 25°C, protect from light and moisture, keep out of reach of children

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