Gabastar 300 mg (Tablet)
Unit Price: ৳ 16.11 (3 x 10: ৳ 483.30)
Strip Price: ৳ 161.10
Medicine Details
| Category | Details |
|---|---|
| Generic | Gabapentin |
| Company | Square pharmaceuticals plc |
| Also available as |
Indications
- Neuropathic Pain
- Adjunctive therapy in partial seizure and secondary generalized seizure
Pharmacology
- Gabapentin is an anti-convulsant
- Structural analog of gamma-amino-butyric-acid (GABA)
- Binds with the alpha-2-delta subunit of voltage gated L-type Calcium channel
- Inhibits branched chain amino acid transferase
- Probably inhibits neurotransmitter release of excitatory amino acid
Dosage
- Initiated with a single 300 mg dose on Day-1
- Titration up to a daily dose of 1800 mg for Neuropathic Pain
- For epilepsy: 900 to 1800 mg/day for patients over 12 years of age
- For pediatric patients age 3-12 years: starting dose should range from 10-15 mg/kg/day
Administration
Oral administration with or without food
Interaction
- Antacids may reduce the bioavailability of Gabastar by up to 20%
- Cimetidine may alter its renal excretion
Contraindications
Hypersensitivity to the drug
Side Effects
- Fatigue
- Dizziness
- Ataxia
- Weight gain
- Peripheral edema
- Dry mouth
- Somnolence
Pregnancy & Lactation
Pregnancy category C. Should be used during pregnancy or lactation only if potential benefits justify potential risks
Precautions & Warnings
Patients advised not to drive or operate machinery until they understand its effects on their mental and/or motor performance
Use in Special Populations
Dose reduction needed for renal impaired patients
Therapeutic Class
Adjunct anti-epileptic drugs
Storage Conditions
Store below 25°C, protect from light and moisture, keep out of reach of children