Eletam 500 mg (Tablet)

Unit Price: ৳ 30.00 (2 x 10: ৳ 600.00)
Strip Price: ৳ 300.00

Medicine Details

Indications

  • treatment of partial-onset seizures
  • monotherapy in adults and adolescents
  • adjunctive therapy in adults, adolescents, children and infants
  • treatment of myoclonic seizures in adults and adolescents
  • treatment of primary generalized tonic-clonic seizures in adults and adolescents

Description

  • precise mechanism unknown
  • minimal activity in submaximal stimulation
  • protection against secondarily generalized activity
  • inhibition of burst firing
  • prevention of hyper synchronization

Dosage

  • recommended starting dose of 250 mg twice daily
  • initial therapeutic dose of 500 mg twice daily
  • maximum dose of 1500 mg twice daily
  • dose adjustment for renal impairment
  • oral solution for infants and children under 6 years

Administration

  • flm-coated tablets
  • taken orally with or without food
  • administered in two equally divided doses

Interaction

  • no influence on serum concentrations of existing antiepileptic medicinal products
  • concomitant administration with probenecid and methotrexate
  • decreased efficacy with osmotic laxative macrogol
  • absorption not altered by food
  • no data on interaction with alcohol

Contraindications

  • hypersensitivity to the active substance or other pyrrolidone derivatives

Side Effects

  • incidence of common adverse reactions
  • adverse reactions in adult and pediatric patients

Pregnancy & Lactation

  • not recommended during pregnancy
  • excretion in human breast milk
  • impact on fertility unknown

Precautions & Warnings

  • dose adjustment for renal impairment
  • association with acute kidney injury
  • cases of decreased blood cell counts
  • risk of suicidal thoughts and behavior
  • paediatric population considerations

Use in Special Populations

  • dose adjustment in elderly patients
  • individualized dose according to renal function
  • no dose adjustment in patients with mild to moderate hepatic impairment

Overdose Effects

  • observed effects of overdose
  • symptomatic treatment
  • haemodialysis in treatment of overdose

Therapeutic Class

  • adjunct anti-epileptic drugs

Storage Conditions

  • store at a cool temperature not exceeding 25°C
  • dry place, protected from light

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