Eletam 500 mg/5 ml (Oral Solution)

100 ml bottle: ৳ 400.00

Medicine Details

Title

Eletam Anti-Epileptic Medicine

Categories

  • Medicine
  • Anti-Epileptic Drugs
  • Pharmaceuticals

Description

Eletam is an anti-epileptic medicine indicated for the treatment of partial-onset seizures in adults, adolescents, and children from 1 month of age. It is also used in the treatment of myoclonic seizures and primary generalized tonic-clonic seizures.

Indications

  • Treatment of partial-onset seizures
  • Adjunctive therapy
  • Treatment of myoclonic seizures
  • Treatment of primary generalized tonic-clonic seizures

Mechanism

The precise mechanism by which Eletam exerts its antiepileptic effect is unknown. It inhibits burst firing without affecting normal neuronal excitability, suggesting it may selectively prevent hyper synchronization of epileptiform burst firing and propagation of seizure activity.

Dosage

  • Recommended starting dose of 250 mg twice daily
  • Maximum dose of 1500 mg twice daily for adults and adolescents
  • Use of oral solution for pediatric population

Administration

The film-coated tablets should be taken orally, swallowed with sufficient quantity of liquid, and may be taken with or without food. The daily dose is administered in two equally divided doses.

Interaction

  • No influence on serum concentrations of existing antiepileptic medicinal products
  • Potential interaction with probenecid, methotrexate, laxatives, food, and alcohol

Contraindications

  • Hypersensitivity to the active substance or other pyrrolidone derivatives or to any of the excipients

SideEffects

  • Common adverse reactions include somnolence, asthenia, infection, dizziness, fatigue, aggression, nasal congestion, decreased appetite, and irritability

PregnancyAndLactation

  • Not recommended during pregnancy and lactation due to excretion in breast milk

SafetyWarnings

  • Renal impairment may require dose adjustment
  • Rare cases of decreased blood cell counts
  • Risk of suicidal thoughts and behavior
  • Tablet formulation not adapted for use in infants and children under the age of 6 years

SpecialPopulations

  • Elderly
  • Renal impairment
  • Hepatic impairment

OverdoseEffects

  • Somnolence
  • Agitation
  • Respiratory depression
  • Coma

TherapeuticClass

Adjunct anti-epileptic drugs

StorageConditions

Store at a cool temperature (not exceeding 25°C) in a dry place, protected from light

Usability

  • Oral intake with or without food
  • Suitable for adults, adolescents, and children from 1 month of age

Formulation

  • Film-coated tablets
  • Oral solution for pediatric population

Efficacy

Minimal activity in submaximal stimulation and threshold tests

SafetyProfile

No specific antidote for Eletam overdose

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