Erata 500 mg (Tablet)

Unit Price: ৳ 30.30 (3 x 10: ৳ 909.00)
Strip Price: ৳ 303.00

Medicine Details

Category Details
Generic Levetiracetam
Company Sandoz a novartis division
Also available as

Indications

  • Monotherapy for partial-onset seizures
  • Adjunctive therapy for partial-onset seizures
  • Adjunctive therapy for myoclonic seizures
  • Adjunctive therapy for primary generalized tonic-clonic seizures

Description

  • Precise mechanism unknown
  • Minimal activity in submaximal stimulation
  • Inhibition of burst firing

Dosage

  • Recommended starting dose for adults and adolescents
  • Maximum dose for adults and adolescents
  • Recommended dose for pediatric population
  • Oral solution for infants and children under 6 years
  • Safety and efficacy not established for children under 16 years
  • Dose adjustment in renal impairment

Administration

  • Oral administration
  • Daily dose in two divided doses

Interaction

  • No influence on serum concentrations of existing antiepileptic medicinal products
  • Interaction with probenecid
  • Concomitant administration with methotrexate
  • Reports of decreased efficacy with concurrent use of osmotic laxative
  • Absorption not altered by food
  • No data on interaction with alcohol

Contraindications

  • Hypersensitivity to active substance or related derivatives

Side Effects

  • Common adverse reactions in adult and pediatric patients

Pregnancy & Lactation

  • Not recommended during pregnancy
  • Excretion in human breast milk

Precautions & Warnings

  • Dose adjustment in renal impairment
  • Rare cases of decreased blood cell counts
  • Monitoring for signs of depression and suicidal ideation
  • Not adapted for use in infants and children under 6 years
  • Impact on learning and growth unknown

Use in Special Populations

  • Adjustment of dose in elderly patients with compromised renal function
  • Individualization of dose according to renal function
  • No dose adjustment in patients with mild to moderate hepatic impairment
  • Recommendation for dose reduction in severe hepatic impairment

Overdose Effects

  • Observation of somnolence, agitation, and respiratory depression
  • No specific antidote
  • Symptomatic treatment
  • Haemodialysis may be considered

Therapeutic Class

  • Adjunct anti-epileptic drugs

Storage Conditions

  • Cool temperature (not exceeding 25°C)
  • Protection from light

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