Iracet 250 mg (Tablet)
Unit Price: ৳ 16.00 (3 x 10: ৳ 480.00)
Strip Price: ৳ 160.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Levetiracetam |
| Company | Square pharmaceuticals plc |
| Also available as |
Indications
- Monotherapy for partial-onset seizures
- Adjunctive therapy for partial-onset seizures with or without generalization
- Treatment of myoclonic seizures in Juvenile Myoclonic Epilepsy
- Treatment of primary generalized tonic-clonic seizures
Description
- Mechanism of antiepileptic effect is unknown
- Minimal activity in submaximal stimulation and threshold tests
- Protection against secondarily generalized activity from focal seizures induced by chemoconvulsants
Dosage
- Recommended starting dose for adults and adolescents from 16 years of age is 250 mg twice daily
- Maximum dose is 1500 mg twice daily
- Different dosages for pediatric population based on age and weight
Administration
- Film-coated tablets to be taken orally with or without food
- Administered in two equally divided doses
Interaction
- No influence on serum concentrations of existing antiepileptic drugs
- Interactions with probenecid, methotrexate, and laxatives reported
- Food and alcohol may slightly alter the rate of absorption
Contraindications
- Hypersensitivity to the active substance or other pyrrolidone derivatives or to any of the excipients
Side Effects
- Common adverse reactions include somnolence, asthenia, infection, dizziness, fatigue, aggression, nasal congestion, decreased appetite, and irritability
Pregnancy & Lactation
- Not recommended during pregnancy and breastfeeding
- Potential impact on fertility unclear
Precautions & Warnings
- Dose adjustment required for renal impairment
- Rare cases of decreased blood cell counts reported
- Risk of suicidal thoughts and behaviors reported
- Tablet formulation not adapted for use in infants and children under 6 years
Use in Special Populations
- Dose adjustment in elderly patients with compromised renal function
- Individualized dose according to renal function in renal impairment
- No dose adjustment needed in patients with mild to moderate hepatic impairment
Overdose Effects
- Symptoms of overdose include somnolence, agitation, aggression, depressed level of consciousness, respiratory depression, and coma
- No specific antidote available
- Symptomatic treatment may include haemodialysis
Therapeutic Class
- Adjunct anti-epileptic drugs
Storage Conditions
- Store at a cool temperature (not exceeding 25°C) and dry place, protected from light