Iracet 500 mg/5 ml (Oral Solution)

50 ml bottle: ৳ 200.61

Medicine Details

Category Details
Generic Levetiracetam
Company Square pharmaceuticals plc
Also available as
Iracet 250 mg tablet Iracet 500 mg tablet Iracet 500 mg injection Iracet xr 500 mg tablet

Indications

  • Monotherapy for partial-onset seizures in adults and adolescents
  • Adjunctive therapy for partial-onset seizures in adults, adolescents, children, and infants
  • Treatment of myoclonic seizures in adults and adolescents with Juvenile Myoclonic Epilepsy
  • Treatment of primary generalized tonic-clonic seizures in adults and adolescents with Idiopathic Generalised Epilepsy

Mechanism of Action

  • Unknown mechanism of exerting antiepileptic effect
  • Minimal activity in submaximal stimulation and threshold tests
  • Inhibition of burst firing without affecting normal neuronal excitability

Dosage

  • Recommended starting dose of 250 mg twice daily for adults and adolescents
  • Initial therapeutic dose of 500 mg twice daily after two weeks
  • Maximum dose of 1500 mg twice daily for adults & adolescents
  • Different dosage requirements for pediatric population

Administration

Oral administration with sufficient liquid, taken with or without food

Interaction

  • No significant influence on serum concentrations of existing antiepileptic drugs
  • Concomitant administration with probenecid, methotrexate, or laxatives may require monitoring
  • No data available for interaction with alcohol

Contraindications

Hypersensitivity to active substance or other pyrrolidone derivatives

Side Effects

  • Common adverse reactions include somnolence, asthenia, infection, dizziness in adults
  • Common adverse reactions include fatigue, aggression, nasal congestion, decreased appetite in pediatric patients

Pregnancy & Lactation

  • Not recommended during pregnancy or breastfeeding unless clinically necessary
  • Excreted in breast milk, breastfeeding not recommended

Precautions & Warnings

  • Dose adjustment required in renal impairment
  • Rare cases of decreased blood cell counts associated with initial treatment
  • Monitoring for signs of depression and suicidal ideation and behaviors
  • Not adapted for use in infants and children under 6 years

Use in Special Populations

  • Dose adjustment recommended for the elderly and patients with compromised renal function

Overdose Effects

  • Observation of somnolence, agitation, aggression, depressed level of consciousness
  • No specific antidote, treatment is symptomatic

Therapeutic Class

Adjunct anti-epileptic drugs

Storage Conditions

Store at a cool temperature not exceeding 25°C, protected from light

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