Leveron 250 mg (Tablet)
Unit Price: ৳ 16.05 (5 x 6: ৳ 481.50)
Strip Price: ৳ 96.30
Medicine Details
Category | Details |
---|---|
Generic | Levetiracetam |
Company | Synovia pharma plc |
Also available as |
Indications
- Monotherapy for partial-onset seizures in adults and adolescents
- Adjunctive therapy for partial-onset seizures in adults, adolescents, children, and infants
- Treatment of myoclonic seizures in adults and adolescents with Juvenile Myoclonic Epilepsy
- Treatment of primary generalized tonic-clonic seizures in adults and adolescents with Idiopathic Generalised Epilepsy
Description
- Precise mechanism(s) unknown
- Minimal activity in submaximal stimulation and threshold tests
- Protection against secondarily generalized activity from focal seizures induced by pilocarpine and kainic acid
- Inhibition of burst firing without affecting normal neuronal excitability
Dosage
- Recommended starting dose for adults and adolescents from 16 years of age
- Initial therapeutic dose for adults and adolescents (≥18 years) and adolescents (12 to 17 years) weighing 50 kg or more
- Pediatric population dosage and monotherapy/adjuvant therapy details
- Administration in two equally divided doses
Administration
- Oral administration
- Swallowed with sufficient quantity of liquid
- May be taken with or without food
Interaction
- No influence on serum concentrations of existing antiepileptic medicinal products
- Interaction with Probenecid, Methotrexate, Laxatives, Food, and Alcohol
Contraindications
- Hypersensitivity to the active substance or other pyrrolidone derivatives or to any of the excipients
Side Effects
- Most common adverse reactions in adult and pediatric patients
Pregnancy & Lactation
- Not recommended during pregnancy and in women of childbearing potential not using contraception unless clinically necessary
- Excretion in human breast milk
- Breastfeeding not recommended
Precautions & Warnings
- Dose adjustment in patients with renal impairment
- Rare cases of decreased blood cell counts
- Association with acute kidney injury
- Monitoring for signs of depression and/or suicidal ideation and behaviors
Use in Special Populations
- Elderly patients with compromised renal function
- Individualization of daily dose according to renal function in elderly patients, patients with renal impairment, and hepatic impairment
Overdose Effects
- Observation of somnolence, agitation, aggression, depressed level of consciousness, respiratory depression, and coma
- No specific antidote
- Induction of emesis
- Hemodialysis
Therapeutic Class
- Adjunct anti-epileptic drugs
Storage Conditions
- Cool temperature (not exceeding 25°C)
- Dry place
- Protected from light
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