Barbit 60 mg (Tablet)
Unit Price: ৳ 1.50 (10 x 10: ৳ 150.00)
Strip Price: ৳ 15.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Phenobarbital |
| Company | Incepta pharmaceuticals ltd |
| Also available as |
Indications
- Sedatives
- Hypnotics for the short-term treatment of insomnia
- Pre-anesthetics
- Long-term anticonvulsants for the treatment of generalized tonic-clonic and cortical local seizures
- Emergency control of certain acute convulsive episodes
Description
- Barbit is a barbiturate
- Nonselective CNS depressant
- Primarily used as a sedative hypnotic and anticonvulsant in subhypnotic doses
Pharmacology
- Acts on GABA receptors
- Increases synaptic inhibition
- Elevates seizure threshold
- Reduces spread of seizure activity
- Likely inhibits calcium channels
- Decreases excitatory transmitter release
- Effects on the polysynaptic midbrain reticular formation
Dosage & Administration
- Pediatric and adult oral and injection dosage recommendations
- Specific doses for preoperative, anticonvulsant, daytime sedative, bedtime hypnotic, and more
- IV injection maximum rate and pediatric dosing for therapeutic levels
Interaction
Concomitant use of Alcohol or other CNS depressants may produce additive CNS depressant effects
Contraindications
Contradicted in patients with known Phenobarbital sensitivity or a history of latent porphyria
Side Effects
- Most common adverse reaction is somnolence
- Less frequent adverse reactions include agitation, confusion, hyperkinesia, and more
Pregnancy & Lactation
Pregnancy Category D; potential fetal damage; caution in nursing women
Precautions & Warnings
- Tolerance and psychological and physical dependence may occur with continuing use
- Administer with caution to patients who are mentally depressed, have suicidal tendencies, or a history of drug abuse
- Caution in patients with hepatic damage
Overdose Effects
- Toxic dose of barbiturates varies considerably
- Manifested by CNS and respiratory depression
- Supportive treatment and immediate hospitalization necessary for treatment
Therapeutic Class
Adjunct anti-epileptic drugs, Barbiturates
Storage Conditions
Keep below 30°C temperature, away from light & moisture; keep out of the reach of children