Barbit Elixir 20 mg/5 ml (Oral Solution)

50 ml bottle: ৳ 43.00

Medicine Details

Indications

  • Sedatives
  • Hypnotics for short-term treatment of insomnia
  • Pre-anesthetics
  • Treatment of generalized tonic-clonic and cortical local seizures
  • Emergency control of certain acute convulsive episodes

Description

  • Barbiturate
  • Nonselective CNS depressant
  • Used as a sedative-hypnotic and anticonvulsant

Pharmacology

  • Acts on GABAA receptors
  • Increases synaptic inhibition
  • Elevates seizure threshold
  • Reduces spread of seizure activity
  • Inhibits calcium channels
  • Decreases excitatory transmitter release
  • Effects on the polysynaptic midbrain reticular formation

Dosage & Administration

  • Pediatric oral dosage
  • Adult oral dosage
  • Pediatric injection dosage
  • Adult injection dosage

Interaction

  • CNS depressants interaction

Contraindications

  • Known sensitivity to Phenobarbital
  • History of latent porphyria

Side Effects

  • Somnolence
  • Agitation
  • Confusion
  • Hyperkinesia
  • CNS depression
  • Nightmares
  • Nervousness
  • Psychiatric disturbance
  • Hallucinations
  • Insomnia
  • Anxiety
  • Dizziness
  • Apnea
  • Bradycardia
  • Hypotension
  • Nausea
  • Vomiting
  • Constipation

Pregnancy & Lactation

  • Pregnancy Category D
  • Fetal damage risk
  • Excretion in milk

Precautions & Warnings

  • Tolerance and dependence
  • Caution in mentally depressed patients
  • Caution in patients with suicidal tendencies
  • Caution in patients with a history of drug abuse
  • Caution in patients with hepatic damage

Overdose Effects

  • Toxic dose variation
  • CNS and respiratory depression
  • Supportive treatment
  • Immediate hospitalization

Therapeutic Class

  • Adjunct anti-epileptic drugs
  • Barbiturates

Storage Conditions

  • Temperature below 30°C
  • Away from light & moisture
  • Keep out of reach of children

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