Emer 20 mg/5 ml (Oral Solution)

100 ml bottle: ৳ 70.00

Medicine Details

Category	Details
Generic	Phenobarbital
Company	Opsonin pharma ltd
Also available as	Emer 30 mg tablet Emer 60 mg tablet Emer 200 mg injection

Title

Emer

Description

Barbiturate, nonselective, central nervous system depressant primarily used as a sedative hypnotic and anticonvulsant.

Indications

Sedatives
Hypnotics
Pre-anesthetics
Anticonvulsants

Pharmacology

Acts on GABA receptors, increasing synaptic inhibition and reducing the spread of seizure activity. Also inhibits calcium channels, resulting in a decrease in excitatory transmitter release.

Dosage & Administration

Pediatric Oral Dosage:
- Preoperative: 1 mg to 3 mg/kg
- Anticonvulsant: 1 mg to 6 mg/kg per day
Adult Oral Dosage:
- Daytime sedative: 30 mg to 120 mg daily in 2 to 3 divided doses
- Bedtime hypnotic: 100 mg to 320 mg
- Anticonvulsant: 50 mg to 100 mg 2 to 3 times daily
Pediatric Injection Dosage:
- 15 to 20 mg/kg IV over 10 to 15 min
- Preoperative Sedation:1 to 3 mg/kg IM/IV
- Anticonvulsant: 4 to 6 mg/kg IM/IV per day
Adult Injection Dosage:
- Insomnia: 100 to 320 mg IM/IV
- Convulsions: 100 to 320 mg IV. Repeat if needed
- Status Epilepticus: 10 to 20 mg/kg IV. Repeat if needed

Interaction

Concomitant use of Alcohol or other CNS depressants may produce additive CNS depressant effects.

Contraindications

Contraindicated in patients with known Phenobarbital sensitivity or a history of latent porphyria.

Side Effects

Somnolence
Agitation
Confusion
Hyperkinesia
Ataxia
Nightmares
Nervousness
Psychiatric disturbance
Hallucinations
Insomnia
Anxiety
Dizziness
Apnea
Bradycardia
Hypotension
Nausea
Vomiting
Constipation

Pregnancy & Lactation

Pregnancy Category D. Can cause fetal damage when administered to a pregnant woman, caution should be taken when administered to a nursing woman.

Precautions & Warnings

Tolerance, psychological and physical dependence may occur with continuing use. Should be administered with caution to patients with mental depression, suicidal tendencies or history of drug abuse. Also caution in patients with hepatic damage.

Overdose Effects

Toxic dose varies. Acute overdosage is manifested by CNS and respiratory depression. Treatment mainly supportive and immediate hospitalization is necessary.