Gabarol 50 mg (Capsule)
Unit Price: ৳ 15.00 (3 x 10: ৳ 450.00)
Strip Price: ৳ 150.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Pregabalin |
| Company | Aci limited |
| Also available as |
Indications
- Neuropathic pain associated with diabetic peripheral neuropathy (DPN)
- Postherpetic neuralgia (PHN)
- Adjunctive therapy for the treatment of partial-onset seizures in patients 1 month of age and older
- Fibromyalgia
- Neuropathic pain associated with spinal cord injury
Pharmacology
- Structural derivative of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA)
- Binds with high affinity to the alpha2-delta site in central nervous system tissues
Dosage
- Maximum recommended dose of Pregabalin is 100 mg three times a day
- Dosing should begin at 50 mg three times a day
- Dose may be increased based on efficacy and tolerability
- Recommended dose of Pregabalin for postherpetic neuralgia is 75 to 150 mg two times a day or 50 to 100 mg three times a day
- Dosage should be adjusted based on individual patient response and tolerability
Administration
- Oral route of administration
- Can be taken with or without food
- Pregabalin CR tablet should be administered after an evening meal
- Should be swallowed whole and not split, crushed, or chewed
Interaction
- Unlikely to be involved in significant pharmacokinetic drug interactions
- No drug interactions with food and others
Contraindications
- Contraindicated in patients with known hypersensitivity to Pregabalin or any of its components
Side Effects
- Common side effects include dizziness, somnolence, dry mouth, edema, blurred vision, weight gain
- In pediatric patients, side effects may include increased weight and increased appetite
Pregnancy & Lactation
- No adequate and well-controlled studies in pregnant women
- Small amounts detected in the milk of lactating women
- Breastfeeding not recommended during treatment
Precautions & Warnings
- Angioedema can occur and may be associated with life threatening respiratory compromise
- Discontinue immediately if hypersensitivity reactions occur
- Increased risk of suicidal thoughts or behavior
- Respiratory depression may occur with concomitant CNS depressants
- May cause dizziness and somnolence, impairing ability to drive or operate machinery
Use in Special Populations
- Safety and effectiveness not established in pediatric patients for certain indications
- Safety and effectiveness in pediatric patients below the age of 1 month not established
Overdose Effects
- Signs and symptoms may include reduced consciousness, depression/anxiety, confusional state, agitation, seizures, heart block
Therapeutic Class
- Adjunct anti-epileptic drugs
- Primary anti-epileptic drugs
Storage Conditions
- Keep in a cool & dry place below 30°C
- Protected from light & moisture
- Keep out of the reach of children
Chemical Structure
- Molecular Formula: C8H17NO2
- Chemical Structure: Image available
Common Questions about Gabarol 50 mg Capsule
- First-line treatment for neuropathic pain, shingles, seizures, and fibromyalgia
- Duration of use depends on improvement in health conditions
- Dosage should be followed as prescribed by the doctor
- Should be taken after food in prescribed dosage
- Storage instructions should be followed to maintain effectiveness
Others
- Route of administration: Oral
- Recommended dose range for various conditions
- Caution with abrupt discontinuation
- No specific antidote for overdose
- No drug interactions reported
- Safety profile in special populations