Gabarol 100 mg (Capsule)
Unit Price: ৳ 25.00 (2 x 10: ৳ 500.00)
Strip Price: ৳ 250.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Pregabalin |
| Company | Aci limited |
| Also available as |
Indications
- Neuropathic pain associated with diabetic peripheral neuropathy (DPN)
- Postherpetic neuralgia (PHN)
- Adjunctive therapy for the treatment of partial-onset seizures in patients 1 month of age and older
- Fibromyalgia
- Neuropathic pain associated with spinal cord injury
Pharmacology
- Structural derivative of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA)
- Binds with high affinity to the alpha2-delta site in central nervous system tissues
- Mechanism of action not fully elucidated
Dosage
- Maximum recommended dose for neuropathic pain associated with diabetic peripheral neuropathy (DPN) is 100 mg three times a day (300 mg/day)
- Recommended dose for postherpetic neuralgia (PHN) is 75 to 150 mg two times a day or 50 to 100 mg three times a day (150 to 300 mg/day)
- Recommended dose for management of fibromyalgia in adults is 300 to 450 mg/day
- Recommended dose range for neuropathic pain associated with spinal cord injury is 150 to 600 mg/day
Administration
- Taken orally with or without food
- Pregabalin CR tablet should be administered after an evening meal
- Should be swallowed whole and should not be split, crushed or chewed
Interaction
- Unlikely to be involved in significant pharmacokinetic drug interactions
Contraindications
- Contraindicated in patients with known hypersensitivity to Pregabalin or any of its components
Side Effects
- Most common side effects in adults are dizziness, somnolence, dry mouth, edema, blurred vision, weight gain and thinking abnormal
- Most common side effects in pediatric patients for the treatment of partial onset seizures are increased weight and increased appetite
Pregnancy & Lactation
- No adequate and well-controlled studies with pregabalin in pregnant women
- Small amounts of pregabalin have been detected in the milk of lactating women
- Breastfeeding not recommended during treatment with pregabalin
Precautions & Warnings
- Angioedema can occur and may be associated with life-threatening respiratory compromise
- Discontinue immediately in cases of angioedema or hypersensitivity reactions
- Antiepileptic drugs, including pregabalin, increase the risk of suicidal thoughts or behavior
- Respiratory depression may occur when used with concomitant CNS depressants
- May cause dizziness and somnolence, impairing ability to drive or operate machinery
- Increased seizure frequency or other adverse reactions may occur if rapidly discontinued
- May cause peripheral edema
Use in Special Populations
- Safety and effectiveness in pediatric patients not established for certain conditions
- Safety and effectiveness of Gabarol extended-release tablet not established in pediatric patients
Overdose Effects
- Signs and symptoms include reduced consciousness, depression/anxiety, confusional state, agitation, restlessness, seizures, and heart block
- No specific antidote
- General supportive care indicated including monitoring of vital signs
Therapeutic Class
- Adjunct anti-epileptic drugs
- Primary anti-epileptic drugs
Storage Conditions
- Keep in a cool & dry place (below 30°C)
- Protected from light & moisture
- Keep out of the reach of children
Chemical Structure
- Molecular Formula: C8H17NO2
- Chemical Structure: Image available
Common Questions about Gabarol 100 mg Capsule
- Considered first-line of treatment for neurotic pain, shingles, seizures, and fibromyalgia
- Duration of use depends on health improvement
- Should be taken as per the prescribed dosage
- Should be taken after food as prescribed
- Storage and disposal instructions provided
- Works differently for different diseases