Lyric 75 mg (Capsule)

Indications

• Neuropathic pain associated with diabetic peripheral neuropathy (DPN)
• Postherpetic neuralgia (PHN)
• Adjunctive therapy for partial-onset seizures in patients
• Fibromyalgia
• Neuropathic pain associated with spinal cord injury

Pharmacology

• Structural derivative of GABA
• Binds to alpha2-delta site in CNS tissues
• Anti-nociceptive effects
• Antiseizure effects

Dosage

• Maximum recommended dose of 100 mg three times a day
• Dosing should begin at 50 mg three times a day
• Maximum recommended dose of 660 mg once daily for PHN
• Dosage range of 300 to 450 mg/day for fibromyalgia
• Starting dose of 150 mg/day for spinal cord injury

Administration

• Oral route of administration
• Can be taken with or without food
• Pregabalin CR tablet should be swallowed whole
• Gradual tapering needed for discontinuation

Interaction

• Unlikely to cause significant pharmacokinetic drug interactions
• No interactions with food and others

Contraindications

• Contraindicated in patients with known hypersensitivity to pregabalin

Side Effects

• Common side effects include dizziness, somnolence, dry mouth, edema
• Weight gain, blurred vision, thinking abnormalities

Pregnancy & Lactation

• Potential risk to fetus
• Small amounts detected in breast milk
• Breastfeeding not recommended

Precautions & Warnings

• Risk of angioedema
• Discontinue immediately in case of severe reactions
• Increased risk of suicidal thoughts or behavior

Use in Special Populations

• Safety and effectiveness not established in pediatric patients
• Lyrica extended-release tablet not studied in pediatrics

Overdose Effects

• Symptoms include reduced consciousness, seizures, heart block
• No specific antidote available

Therapeutic Class

• Adjunct anti-epileptic drugs
• Primary anti-epileptic drugs

Storage Conditions

• Keep in cool & dry place
• Protect from light & moisture
• Keep out of reach of children

Chemical Structure

• Molecular formula: C8H17NO2
• Chemical structure image available

Common Questions

• What is Lyrica 75 mg Capsule?
• How long to use before seeing improvement?
• Frequency of use
• Storage and disposal instructions
• Specific effects for each disease

Drug Interactions

• Unlikely to have significant pharmacokinetic interactions
• No interactions with food

Pediatric Uses

• Safety and effectiveness not established for various conditions

Route of Administration

• Oral route with or without food
• Pregabalin CR tablet after evening meal

Maximum Recommended Dose

• 100 mg three times a day
• 660 mg once daily for PHN

Starting Dosage

• 50 mg three times a day
• 150 mg/day for fibromyalgia
• 150 mg two times a day for spinal cord injury

Discontinuation

• Gradual tapering over a minimum of 1 week

Risk factors

• Angioedema risk
• Hypersensitivity reactions

Pediatric Safety

• Not established for multiple conditions

Common Side Effects

• Dizziness
• Dry mouth
• Edema

Alternative Medication

• Anticonvulsants
• Treatment for neurotic pain, shingles, seizures, fibromyalgia

Use Duration

• Depends on the health condition
• Consult doctor for guidance

Specific Instructions

• Swallow whole, do not split/crush/chew
• Take after evening meal
• Dosage adjustment based on individual response

Symptoms of Overdose

• Reduced consciousness
• Agitation
• Heart block

Antidote

• General supportive care
• Vital signs monitoring

Chemical Formula

• C8H17NO2

Allergies

• Hypersensitivity to pregabalin or its components

Pediatric Safety Information

• Lack of data for various conditions

Monitoring

• Dosage adjustments as needed
• Monitor for withdrawal symptoms

Recommended Dosage Range

• 150 to 600 mg/day for spinal cord injury

Duration of Treatment

• Varies by condition
• Consult physician for guidance

Weight Gain

• Potential side effect

Vision Changes

• Blurred vision possible

Storage Instructions

• Cool & dry place
• Protect from light & moisture

Special Populations

• Safety not established in pediatric patients
• Avoid in lactating women

Treatment Duration

• Continuation based on physician's advice

Driving Precautions

• May cause dizziness and somnolence

Dosing Frequency

• As prescribed by healthcare provider

Pediatric Dosing

• Safety not established for multiple conditions

Drug Class

• Adjunct anti-epileptic
• Primary anti-epileptic

Frequent Side Effects

• Dizziness
• Dry mouth
• Weight gain

Adverse Reactions

• Potential for angioedema
• Risk of hypersensitivity reactions

Safety Information

• Risk of angioedema
• Hypersensitivity reactions may occur

Dosing Recommendations

• Gradual titration based on response

Duration of Therapy

• Depends on the condition being treated

Consultation

• Discuss with healthcare provider

Pediatric Data

• Limited safety information available

Swallowing Instructions

• Swallow whole, do not chew or crush

Administration Timing

• Pregabalin CR tablet after evening meal

Pediatric Safety Data

• Insufficient data for pediatric use

Risk Assessment

• Considerations for angioedema risk

Emergency Situations

• Immediate discontinuation in severe reactions

Seizure Management

• Dosage adjustments required for seizure control

Gradual Tapering

• Taper off medication over at least 1 week

Infant Safety

• Effectiveness not established in infants

Monitoring Requirements

• Close monitoring for adverse reactions

Route of Intake

• Oral administration
• With or without food

Therapeutic Classification

• Adjunct anti-epileptic
• Primary anti-epileptic

Usual Dosage

• 100 mg three times a day as maximum dose

Maximum Tolerated Dose

• 660 mg once daily for PHN

Starting Dose Level

• 50 mg three times a day
• 150 mg/day for fibromyalgia

Specific Precautions

• Risk of angioedema and hypersensitivity reactions

Safety Data

• Limited safety data in pediatric patients

Withdrawal Process

• Gradual tapering over a minimum of 1 week

Consultation Required

• Discuss with healthcare provider for dosing instructions

Overconsumption Effects

• Symptoms include reduced consciousness and seizures

Monitoring Guidelines

• Monitor for side effects and adjust dosages accordingly

Related Brands

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