Nervalin 75 mg (Capsule)

Unit Price: ৳ 20.00 (3 x 10: ৳ 600.00)
Strip Price: ৳ 200.00

Medicine Details

Category Details
Generic Pregabalin
Company Beximco pharmaceuticals ltd
Also available as
Nervalin 50 mg capsule Nervalin 25 mg capsule Nervalin cr 330 mg tablet Nervalin 100 mg oral solution Nervalin cr 825 mg tablet Nervalin cr 165 mg tablet

Indications

  • Neuropathic pain associated with diabetic peripheral neuropathy
  • Postherpetic neuralgia
  • Adjunctive therapy for the treatment of partial-onset seizures
  • Fibromyalgia
  • Neuropathic pain associated with spinal cord injury

Pharmacology

  • Structural derivative of the inhibitory neurotransmitter gamma-aminobutyric acid
  • Binds with high affinity to the alpha2-delta site in central nervous system tissues
  • Anti-nociceptive and antiseizure effects

Dosage

  • Maximum recommended dose of 100 mg three times a day for neuropathic pain associated with diabetic peripheral neuropathy
  • Recommended dose of 75 to 150 mg two times a day for postherpetic neuralgia
  • Recommended dose of 300 to 450 mg/day for fibromyalgia
  • Recommended dose range of 150 to 600 mg/day for neuropathic pain associated with spinal cord injury

Administration

  • Oral route of administration
  • Can be taken with or without food
  • Pregabalin CR tablet should be administered after an evening meal
  • Should be swallowed whole and should not be split, crushed or chewed

Interaction

  • Unlikely to be involved in significant pharmacokinetic drug interactions

Contraindications

  • Contraindicated in patients with known hypersensitivity to Pregabalin or any of its components

Side Effects

  • Dizziness
  • Somnolence
  • Dry mouth
  • Edema
  • Blurred vision
  • Weight gain
  • Thinking abnormal
  • Increased weight
  • Increased appetite

Pregnancy & Lactation

  • No adequate and well-controlled studies in pregnant women
  • Potential risk to a fetus
  • Small amounts detected in the milk of lactating women
  • Breastfeeding not recommended

Precautions & Warnings

  • Angioedema can occur and may be associated with life-threatening respiratory compromise
  • Hypersensitivity reactions
  • Increased risk of suicidal thoughts or behavior
  • Respiratory depression may occur when used with concomitant CNS depressants
  • May cause dizziness and somnolence
  • Increased seizure frequency or other adverse reactions if rapidly discontinued
  • May cause peripheral edema
  • Caution when coadministering with thiazolidinedione antidiabetic agents

Use in Special Populations

  • Safety and effectiveness not established in pediatric patients for various indications
  • Safety and effectiveness not established in pediatric patients below the age of 1 month for adjunctive therapy for partial onset seizures
  • Safety and effectiveness of Nervalin extended-release tablet not established in pediatric patients

Overdose Effects

  • Signs and symptoms include reduced consciousness, depression/anxiety, confusional state, agitation, restlessness, seizures, and heart block
  • No specific antidote
  • General supportive care indicated, including monitoring of vital signs

Therapeutic Class

  • Adjunct anti-epileptic drugs
  • Primary anti-epileptic drugs

Storage Conditions

  • Keep in a cool & dry place (below 30°C)
  • Protected from light & moisture
  • Keep out of the reach of children

Chemical Structure

  • Molecular Formula: C8H17NO2

Common Questions about Nervalin 75 mg Capsule

  • First-line treatment for neurotic pain, shingles, seizures, and fibromyalgia
  • Duration of use depends on improvement in health condition
  • Should be taken in prescribed dosage after food
  • Instructions for storage and disposal: Keep in a cool dry place and in its original packaging, out of the reach of children and pets
  • Works differently for different diseases
  • Consult the doctor before stopping the medication
  • Can be used with Diazepam
  • May cause weight gain and increased hunger

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