Neugaba 75 mg (Capsule)

Unit Price: ৳ 18.00 (3 x 10: ৳ 540.00)
Strip Price: ৳ 180.00

Medicine Details

Indications

  • Neuropathic pain associated with diabetic peripheral neuropathy (DPN)
  • Postherpetic neuralgia (PHN)
  • Adjunctive therapy for the treatment of partial-onset seizures in patients 1 month of age and older
  • Fibromyalgia
  • Neuropathic pain associated with spinal cord injury

Pharmacology

  • Structural derivative of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA)
  • Binds with high affinity to the alpha2-delta site in central nervous system tissues
  • Anti-nociceptive and antiseizure effects

Dosage

  • Maximum recommended dose is 100 mg three times a day for DPN
  • Recommended dose of 75 to 150 mg two times a day for PHN
  • 300 to 450 mg/day for fibromyalgia
  • 150 to 600 mg/day for neuropathic pain associated with spinal cord injury

Administration

  • Oral route of administration
  • Can be taken with or without food
  • Pregabalin CR tablet should be administered after an evening meal

Interaction

  • Unlikely to be involved in significant pharmacokinetic drug interactions
  • Not applicable for drug interaction with food and others

Contraindications

  • Contraindicated in patients with known hypersensitivity to Pregabalin or any of its components

Side Effects

  • Dizziness
  • Somnolence
  • Dry mouth
  • Edema
  • Blurred vision
  • Weight gain
  • Difficulty with concentration/attention

Pregnancy & Lactation

  • No adequate and well-controlled studies in pregnant women
  • Potential risk to a fetus
  • Small amounts detected in the milk of lactating women
  • Breastfeeding is not recommended during treatment

Precautions & Warnings

  • Angioedema can occur and may be associated with life-threatening respiratory compromise
  • Discontinue immediately in case of hypersensitivity reactions
  • Increase the risk of suicidal thoughts or behavior
  • Respiratory depression may occur when used with concomitant CNS depressants
  • May cause dizziness and somnolence
  • Caution should be exercised when coadministering with thiazolidinedione antidiabetic agents

Use in Special Populations

  • Safety and effectiveness not established in pediatric patients for various indications
  • Safety and effectiveness not established in pediatric patients below the age of 1 month for adjunctive therapy for partial onset seizures
  • Safety and effectiveness not established for Neugaba extended-release tablet in pediatric patients

Overdose Effects

  • Signs and symptoms include reduced consciousness, depression/anxiety, confusional state, agitation, restlessness, seizures, and heart block
  • No specific antidote
  • General supportive care indicated including monitoring of vital signs

Therapeutic Class

  • Adjunct anti-epileptic drugs
  • Primary anti-epileptic drugs

Storage Conditions

  • Keep in a cool & dry place (below 30°C)
  • Protected from light & moisture
  • Keep out of the reach of children

Chemical Structure

  • Molecular Formula: C8H17NO2

Common Questions about Neugaba 75 mg Capsule

  • First-line treatment for neurotic pain, shingles, seizures, and fibromyalgia
  • Frequency and duration of use as prescribed by the doctor
  • Must be taken after food in a prescribed dosage
  • Storage and disposal instructions
  • Works differently for different diseases
  • Consult the doctor before stopping the medication

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