Neurega 25 mg (Capsule)
Medicine Details
| Category | Details |
|---|---|
| Generic | Pregabalin |
| Company | Ibn sina pharmaceuticals ltd |
| Also available as |
Title
Neurega 25 mg Capsule
Categories
- Pain management
- Neuropathic pain
- Anti-epileptic
Description
Neurega is indicated for neuropathic pain associated with diabetic peripheral neuropathy (DPN), postherpetic neuralgia (PHN), fibromyalgia, neuropathic pain associated with spinal cord injury, and adjunctive therapy for the treatment of partial-onset seizures.
Indications
Neuropathic pain associated with diabetic peripheral neuropathy, postherpetic neuralgia, fibromyalgia, neuropathic pain associated with spinal cord injury, adjunctive therapy for the treatment of partial-onset seizures
Pharmacology
Pregabalin is a structural derivative of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA) and binds with high affinity to the alpha2-delta site in central nervous system tissues.
Dosage
Dosage varies for different conditions, with maximum recommended doses for adults and dosing adjustment based on efficacy and tolerability.
Administration
- Route of administration: Oral route, with or without food for Pregabalin, after an evening meal for Pregabalin CR tablet. Swallowed whole, not split, crushed, or chewed.
- Discontinuation guidelines: Gradual tapering over a minimum of 1 week when discontinuing both Pregabalin and Pregabalin CR
Interaction
- Drug interaction: Unlikely to be involved in significant pharmacokinetic drug interactions
- Food and others interaction: Not applicable
Contraindications
Contraindicated in patients with known hypersensitivity to Pregabalin or any of its components
Side effects
- Dizziness
- Somnolence
- Dry mouth
- Edema
- Blurred vision
- Weight gain
- Cognitive impairment
- Increased weight
- Increased appetite
Pregnancy and lactation
- Pregnancy: No adequate and well-controlled studies, potential risk to fetus
- Lactation: Small amounts detected in the milk of lactating women, not recommended during treatment
Precautions and warnings
- Adverse effects: Angioedema, hypersensitivity reactions, increased risk of suicidal thoughts or behavior, respiratory depression, dizziness, somnolence, potential peripheral edema
Pediatric use
Safety and effectiveness in pediatric patients not established for certain conditions and age groups.
Overdose effects
May cause reduced consciousness, depression/anxiety, confusional state, agitation, restlessness, seizures, heart block. No specific antidote.
Therapeutic class
- Adjunct anti-epileptic drugs
- Primary anti-epileptic drugs
Storage conditions
Keep in a cool & dry place (below 30°C), protected from light & moisture, and out of the reach of children
Chemical structure
- Molecular formula: C8H17NO2
- Chemical image link: https://medex.com.bd/storage/res/g-res-919-pregabalin-chemical-structure-dKjKzfuVRrNkwNMBalNK.svg
Common questions
- What is it: An anticonvulsant considered the first-line treatment for neuropathic pain, shingles, seizures, and fibromyalgia
- Improvement duration: To be taken until improvement is seen
- Usage frequency: As prescribed by the doctor
- Food instructions: Should be taken after food in the prescribed dosage
- Storage disposal instructions: Kept in a cool dry place, in its original packaging, and unreachable to children and pets
- Disease variation: Works differently for different diseases
- Duration of use: Depends on the specific condition, advised to consult the doctor
- Continuation when feeling fine: Should not be stopped even if feeling fine, doctor's consultation advised
- Combination with diazepam: Can be used together
- Potential weight gain: May cause weight gain, consultation with a dietician recommended
- Quick tips:
- To be taken as per the dose and duration prescribed by your doctor
- May cause sleepiness, be cautious with activities requiring concentration
- May cause blurring or loss of vision, immediate doctor consultation required
- Inform your doctor about any unusual changes in mood or behavior
- Do not stop suddenly without consulting your doctor