Pegalin 50 mg (Capsule)
Unit Price: ৳ 15.00 (5 x 10: ৳ 750.00)
Strip Price: ৳ 150.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Pregabalin |
| Company | Popular pharmaceuticals ltd |
| Also available as |
Indications
- Neuropathic pain associated with diabetic peripheral neuropathy (DPN)
- Postherpetic neuralgia (PHN)
- Adjunctive therapy for the treatment of partial-onset seizures in patients 1 month of age and older
- Fibromyalgia
- Neuropathic pain associated with spinal cord injury
Pharmacology
Pregabalin is a structural derivative of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA). It binds with high affinity to the alpha2-delta site in central nervous system tissues.
Dosage
- Maximum recommended dose: 100 mg three times a day for neuropathic pain associated with diabetic peripheral neuropathy
- Recommended dose for postherpetic neuralgia: 75 to 150 mg two times a day
- Recommended dose for fibromyalgia: 300 to 450 mg/day
- Recommended dose range for neuropathic pain associated with spinal cord injury: 150 to 600 mg/day
Administration
- Route of administration: Oral
- Special instruction for Pregabalin CR tablet administration: Swallowed whole after an evening meal
Interaction
- Drug interaction with medication: Unlikely to be involved in significant pharmacokinetic drug interactions
Contraindications
Contraindicated in patients with known hypersensitivity to Pregabalin or any of its components
Side Effects
- Dizziness
- Somnolence
- Dry mouth
- Edema
- Blurred vision
- Weight gain
- Difficulty with concentration/attention (thinking abnormal)
- Increased weight and increased appetite in pediatric patients
Pregnancy & Lactation
- Pregnancy: No adequate and well-controlled studies, potential risk to fetus
- Lactation: Small amounts detected in the milk, not recommended during treatment
Precautions & Warnings
- Angioedema and hypersensitivity reactions may occur
- Increased risk of suicidal thoughts or behavior
- Respiratory depression may occur when used with concomitant CNS depressants
- May cause dizziness and somnolence, impairing ability to drive or operate machinery
- Increased seizure frequency or other adverse reactions upon rapid discontinuation
- Possible peripheral edema
- Caution when coadministering with thiazolidinedione antidiabetic agents
Use in Special Populations
- Use in children and adolescents: Safety and effectiveness not established in various conditions
Overdose Effects
Signs and symptoms include reduced consciousness, depression/anxiety, seizures, and heart block. No specific antidote.
Therapeutic Class
- Adjunct anti-epileptic drugs
- Primary anti-epileptic drugs
Storage Conditions
Keep in a cool & dry place (below 30°C), protected from light & moisture. Keep out of the reach of children.
Chemical Structure
- Molecular Formula: C8H17NO2
- Chemical Structure Image: URL to chemical structure image
Common Questions about Pegalin 50 mg Capsule
- What is Pegalin 50 mg Capsule?: An anticonvulsant used for neurotic pain, shingles, seizures, and fibromyalgia
- Frequency of Use: As prescribed by the doctor
- Instructions for Storage and Disposal: Keep in a cool dry place and in its original packaging, out of reach of children and pets
- Effectiveness for Different Diseases: Works in different ways for different diseases