Pegaron 75 mg (Capsule)

Indications

• Neuropathic pain associated with diabetic peripheral neuropathy (DPN)
• Postherpetic neuralgia (PHN)
• Adjunctive therapy for the treatment of partial-onset seizures in patients 1 month of age and older
• Fibromyalgia
• Neuropathic pain associated with spinal cord injury

Pharmacology

• Structural derivative of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA)
• Binds with high affinity to the alpha2-delta site in central nervous system tissues

Dosage

• Maximum recommended dose of Pregabalin is 100 mg three times a day for DPN patients
• Recommended dose of Pregabalin is 75 to 150 mg two times a day for PHN patients
• Recommended dose of Pregabalin is 300 to 450 mg/day for fibromyalgia patients
• Recommended dose range of Pregabalin is 150 to 600 mg/day for spinal cord injury patients
• Pregabalin CR capsule dose varies based on total daily dose of Pregabalin tablet

Administration

• Oral route of administration
• Can be taken with or without food
• Pregabalin CR tablet should be administered after an evening meal

Interaction

• Unlikely to be involved in significant pharmacokinetic drug interactions

Contraindications

• Contraindicated in patients with known hypersensitivity to Pregabalin or any of its components

Side Effects

• Most common side effects in adults: dizziness, somnolence, dry mouth, edema, blurred vision, weight gain, thinking abnormal
• Most common side effects in pediatric patients: increased weight, increased appetite

Pregnancy & Lactation

• No adequate and well-controlled studies in pregnant women
• Small amounts detected in the milk of lactating women
• Breastfeeding not recommended due to potential risk of tumorigenicity

Precautions & Warnings

• Angioedema can occur and may be associated with life-threatening respiratory compromise requiring emergency treatment
• Increased risk of suicidal thoughts or behavior
• Respiratory depression may occur when used with concomitant CNS depressants

Use in Special Populations

• Safety and effectiveness not established in pediatric patients for several indications

Overdose Effects

• Signs and symptoms include reduced consciousness, depression/anxiety, seizures, heart block

Therapeutic Class

• Adjunct anti-epileptic drugs, Primary anti-epileptic drugs

Storage Conditions

• Keep in a cool & dry place (below 30°C), protected from light & moisture
• Keep out of the reach of children

Chemical Structure

• Molecular Formula: C8H17NO2
• Chemical Structure: Structured image

Common Questions about Pegaron 75 mg Capsule

• First-line treatment for neurotic pain, shingles, seizures, and fibromyalgia
• Duration of consumption depends on health conditions
• Dosage as prescribed by the doctor
• Should be taken after food in a prescribed dosage
• Instructions for storage and disposal
• Works differently for different diseases
• Duration depends on the condition
• Should not be stopped suddenly
• Can be used with Diazepam
• May cause weight gain
• Quick tips for consumption

Related Brands

• GABA-P 50 mg (Capsule) - renata-limited
• GABA-P 75 mg (Capsule) - renata-limited
• Gabarol 25 mg (Capsule) - aci-limited
• Gabarol 50 mg (Capsule) - aci-limited
• Gabarol 75 mg (Capsule) - aci-limited