PG 75 mg (Capsule)
Unit Price: ৳ 19.00 (3 x 10: ৳ 570.00)
Strip Price: ৳ 190.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Pregabalin |
| Company | Eskayef pharmaceuticals ltd |
| Also available as |
Indications
- Neuropathic pain associated with diabetic peripheral neuropathy (DPN)
- Postherpetic neuralgia (PHN)
- Adjunctive therapy for the treatment of partial-onset seizures in patients 1 month of age and older
- Fibromyalgia
- Neuropathic pain associated with spinal cord injury
Pharmacology
Structural derivative of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA). Binds with high affinity to the alpha2-delta site in central nervous system tissues.
Dosage
- Maximum recommended dose for neuropathic pain associated with diabetic peripheral neuropathy is 300 mg/day
- Recommended dose for postherpetic neuralgia is 150 to 300 mg/day
- Recommended dose for fibromyalgia is 300 to 450 mg/day
- Recommended dose range for neuropathic pain associated with spinal cord injury is 150 to 600 mg/day
- When switching from Pregabalin capsules to Pregabalin CR capsule, dose conversion should be done as per provided information
- Different dose conversions for Pregabalin tablets to Pregabalin CR capsules
Administration
- Route: Oral
- Instructions:
- Can be taken with or without food
- Pregabalin CR tablet should be administered after an evening meal
- Should be swallowed whole and should not be split, crushed or chewed
- Gradual tapering is recommended when discontinuing the medication
Interaction
- Medication: Unlikely to be involved in significant pharmacokinetic drug interactions
- FoodAndOthers: Not applicable
Contraindications
Contraindicated in patients with known hypersensitivity to Pregabalin or any of its components
Side Effects
- Dizziness
- Somnolence
- Dry mouth
- Edema
- Blurred vision
- Weight gain
- Thinking abnormal (primarily difficulty with concentration/attention)
- Increased weight and increased appetite in pediatric patients
PregnancyAndLactation
- Pregnancy: No adequate and well-controlled studies with pregabalin in pregnant women
- Lactation: Small amounts of pregabalin have been detected in the milk of lactating women. Breastfeeding is not recommended during treatment with pregabalin due to potential risk of tumorigenicity
PrecautionsAndWarnings
- Angioedema and hypersensitivity reactions may occur, requiring immediate discontinuation
- Increased risk of suicidal thoughts or behavior
- Respiratory depression may occur when used with concomitant CNS depressants
- May cause dizziness, somnolence, and impair patients' ability to drive or operate machinery
- Increased seizure frequency or adverse reactions may occur if rapidly discontinued
- May cause peripheral edema
- Cautious administration when coadministering with thiazolidinedione antidiabetic agents
UseInSpecialPopulations
Safety and effectiveness have not been established in pediatric patients for various indications
OverdoseEffects
Signs and symptoms include reduced consciousness, depression/anxiety, confusional state, agitation, restlessness, seizures, and heart block. No specific antidote. General supportive care is indicated.
TherapeuticClass
- Adjunct anti-epileptic drugs
- Primary anti-epileptic drugs
StorageConditions
Keep in a cool & dry place, protected from light & moisture. Keep out of the reach of children.
ChemicalStructure
- MolecularFormula: C8H17NO2
- ChemicalStructureImage: https://medex.com.bd/storage/res/g-res-919-pregabalin-chemical-structure-dKjKzfuVRrNkwNMBalNK.svg
CommonQuestions
- What is PG 75 mg Capsule?
- How long do I need to use PG 75 mg Capsule before I see improvement in my condition?
- At what frequency do I need to use PG 75 mg Capsule?
- Should I use PG 75 mg Capsule empty stomach, before food or after food?
- What are the instructions for the storage and disposal of PG 75 mg Capsule?
- Does PG 75 mg Capsule work in the same way for each disease?
- How long do I need to take PG 75 mg Capsule?
- Is it necessary to continue taking PG 75 mg Capsule even if I feel fine?
- Can I take Diazepam and PG 75 mg Capsule together?
- Can the use of PG 75 mg Capsule cause weight gain?
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