Prebalin 50 mg (Capsule)
Unit Price: ৳ 15.00 (3 x 10: ৳ 450.00)
Strip Price: ৳ 150.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Pregabalin |
| Company | General pharmaceuticals ltd |
| Also available as |
Indications
- Neuropathic pain associated with diabetic peripheral neuropathy (DPN)
- Postherpetic neuralgia (PHN)
- Adjunctive therapy for the treatment of partial-onset seizures in patients 1 month of age and older
- Fibromyalgia
- Neuropathic pain associated with spinal cord injury
Pharmacology
- Structural derivative of gamma-aminobutyric acid
- Binds with high affinity to the alpha2-delta site
Dosage
- Maximum recommended dose of Pregabalin is 100 mg three times a day
- Recommended dose of Pregabalin is 75 to 150 mg two times a day or 50 to 100 mg three times a day
- Recommended dose of Pregabalin for fibromyalgia is 300 to 450 mg/day
- Recommended dose range of Pregabalin for neuropathic pain associated with spinal cord injury is 150 to 600 mg/day
Administration
- Oral route of administration
- Can be taken with or without food
- Pregabalin CR tablet should be administered after an evening meal
- Should be swallowed whole and not be split, crushed, or chewed
- Gradual tapering over a minimum of 1 week when discontinuing
Interaction
- Unlikely to be involved in significant pharmacokinetic drug interactions
Contraindications
- Contraindicated in patients with known hypersensitivity to Pregabalin or any of its components
Side Effects
- Dizziness
- Somnolence
- Dry mouth
- Edema
- Blurred vision
- Weight gain
- Difficulty with concentration/attention
Pregnancy & Lactation
- No adequate and well-controlled studies in pregnant women
- Small amounts detected in the milk of lactating women
- Breastfeeding not recommended
Precautions & Warnings
- Angioedema can occur
- Hypersensitivity reactions
- Increased risk of suicidal thoughts or behavior
- Respiratory depression may occur
- May cause dizziness and somnolence
- Increased seizure frequency may occur if rapidly discontinued
- Caution when coadministering with thiazolidinedione antidiabetic agents
Use in Special Populations
- Safety and effectiveness not established in pediatric patients for certain indications
- Safety and effectiveness not established in pediatric patients below the age of 1 month for adjunctive therapy for partial onset seizures
- Safety and effectiveness of Prebalin extended-release tablet not established in pediatric patients
Overdose Effects
- Reduced consciousness
- Depression/anxiety
- Seizures and heart block reported
Therapeutic Class
- Adjunct anti-epileptic drugs
- Primary anti-epileptic drugs
Storage Conditions
- Keep in a cool & dry place (below 30°C)
- Protected from light & moisture
- Keep out of the reach of children
Chemical Structure
- Molecular Formula: C8H17NO2
Common Questions about Prebalin 50 mg Capsule
- First-line treatment for neurotic pain, shingles, seizures, and fibromyalgia
- Duration of use depends on improvement in health conditions
- Frequency of use should be as prescribed by the doctor
- Should be taken after food in a prescribed dosage
- Instructions for storage and disposal provided
- Works differently for different diseases
- Duration of use depends on the condition
- Necessary to continue taking even if feeling fine
- Can be used with Diazepam
- May cause weight gain
- Precautions and tips provided