Pregaba 50 mg (Capsule)
Unit Price: ৳ 15.00 (3 x 10: ৳ 450.00)
Strip Price: ৳ 150.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Pregabalin |
| Company | Opsonin pharma ltd |
| Also available as |
Indications
- Neuropathic pain associated with diabetic peripheral neuropathy (DPN)
- Postherpetic neuralgia (PHN)
- Adjunctive therapy for the treatment of partial-onset seizures in patients 1 month of age and older
- Fibromyalgia
- Neuropathic pain associated with spinal cord injury
Pharmacology
- Structural derivative of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA)
- Binds with high affinity to the alpha2-delta site in central nervous system tissues
- Anti-nociceptive and antiseizure effects
Dosage
- Maximum recommended dose of Pregabalin is 100 mg three times a day for adults with DPN
- Recommended dose for PHN is 75 to 150 mg two times a day
- Recommended dose for management of fibromyalgia is 300 to 450 mg/day
Route of Administration
Oral
Drug Interaction
- Unlikely to be involved in significant pharmacokinetic drug interactions
Contraindications
Patients with known hypersensitivity to Pregabalin or any of its components
Side Effects
- Dizziness
- Somnolence
- Dry mouth
- Edema
- Blurred vision
- Weight gain
- Difficulty with concentration/attention
Pregnancy & Lactation
- No adequate and well-controlled studies in pregnant women
- Small amounts detected in the milk of lactating women
- Breastfeeding not recommended
Precautions & Warnings
- Angioedema
- Hypersensitivity reactions
- Increased risk of suicidal thoughts or behavior
- Respiratory depression
- May cause dizziness and somnolence
- Increased seizure frequency if rapidly discontinued
- May cause peripheral edema
- Caution when coadministering with thiazolidinedione antidiabetic agents
Use in Special Populations
- Safety and effectiveness not established in pediatric patients for certain conditions
- Safety and effectiveness not established for pediatric patients below the age of 1 month for adjunctive therapy for partial onset seizures
Overdose Effects
- Reduced consciousness
- Depression/anxiety
- Confusional state
- Agitation and restlessness
- Seizures
- Heart block
Therapeutic Class
- Adjunct anti-epileptic drugs
- Primary anti-epileptic drugs
Storage Conditions
Keep in a cool & dry place (below 30°C), protected from light & moisture
Chemical Structure
- Molecular Formula: C8H17NO2
Commonly Asked Questions
- First-line treatment for neurotic pain, shingles, seizures, and fibromyalgia
- Usage duration varies for different conditions
- Should be taken after food
- Storage and disposal instructions
- Works differently for different diseases
- Consultation before discontinuation
- Potential weight gain
- Quick tips