Pregaba 150 mg (Capsule)

Unit Price: ৳ 35.00 (3 x 10: ৳ 1,050.00)
Strip Price: ৳ 350.00

Medicine Details

Indications

  • Neuropathic pain associated with diabetic peripheral neuropathy (DPN)
  • Postherpetic neuralgia (PHN)
  • Adjunctive therapy for the treatment of partial-onset seizures in patients 1 month of age and older
  • Fibromyalgia
  • Neuropathic pain associated with spinal cord injury

Pharmacology

  • Structural derivative of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA)
  • Binds with high affinity to the alpha2-delta site in central nervous system tissues
  • Anti-nociceptive and antiseizure effects

Dosage

  • Maximum dose of 100 mg three times a day for diabetic peripheral neuropathy (DPN)
  • Recommended dose of 75 to 150 mg two times a day for postherpetic neuralgia (PHN)
  • Recommended dose range of 150 to 600 mg/day for neuropathic pain associated with spinal cord injury
  • Dosing should begin at 75 mg two times a day for fibromyalgia
  • Maximum recommended dose of 660 mg once daily for Pregabalin CR capsule

Administration

  • Oral administration
  • Can be taken with or without food
  • Pregabalin CR tablet should be administered after an evening meal
  • Should be swallowed whole and should not be split, crushed or chewed

Drug Interaction

  • Unlikely to be involved in significant pharmacokinetic drug interactions

Contraindications

  • Contraindicated in patients with known hypersensitivity to Pregabalin or any of its components

Side Effects

  • Dizziness
  • Somnolence
  • Dry mouth
  • Edema
  • Blurred vision
  • Weight gain
  • Difficulty with concentration/attention
  • Increased weight and increased appetite in pediatric patients

Pregnancy & Lactation

  • No adequate and well-controlled studies in pregnant women
  • Small amounts detected in the milk of lactating women
  • Breastfeeding not recommended

Precautions & Warnings

  • Angioedema can occur and may be associated with life-threatening respiratory compromise
  • Increased risk of suicidal thoughts or behavior
  • Respiratory depression may occur when used with concomitant CNS depressants
  • May cause dizziness and somnolence, impairing driving or operating machinery

Use in Special Populations

  • Safety and effectiveness not established in pediatric patients for certain indications
  • Safety and effectiveness not established in pediatric patients below the age of 1 month for adjunctive therapy for partial onset seizures

Overdose Effects

  • Reduced consciousness
  • Depression/anxiety
  • Confusional state
  • Seizures
  • Heart block
  • No specific antidote

Therapeutic Class

  • Adjunct anti-epileptic drugs
  • Primary anti-epileptic drugs

Storage Conditions

  • Keep in a cool & dry place (below 30°C)
  • Protected from light & moisture
  • Keep out of the reach of children

Chemical Structure

  • Molecular Formula: C8H17NO2
  • Chemical Structure Image: [Link to image]

Common Questions

  • What is Pregaba 150 mg Capsule?
  • How long do I need to use Pregaba 150 mg Capsule before I see improvement?
  • At what frequency do I need to use Pregaba 150 mg Capsule?
  • Should I use Pregaba 150 mg Capsule empty stomach, before food or after food?
  • What are the instructions for the storage and disposal of Pregaba 150 mg Capsule?
  • Does Pregaba 150 mg Capsule work in the same way for each disease?
  • How long do I need to take Pregaba 150 mg Capsule?
  • Is it necessary to continue taking Pregaba 150 mg Capsule even if I feel fine?
  • Can I take Diazepam and Pregaba 150 mg Capsule together?
  • Can the use of Pregaba 150 mg Capsule cause weight gain?
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