Pregaben 50 mg (Capsule)

Unit Price: ৳ 13.75 (3 x 10: ৳ 412.50)
Strip Price: ৳ 137.50

Medicine Details

Category Details
Generic Pregabalin
Company Incepta pharmaceuticals ltd
Also available as
Pregaben 75 mg capsule Pregaben 150 mg capsule Pregaben 25 mg capsule Pregaben 100 mg oral solution Pregaben cr 825 mg tablet Pregaben cr 165 mg tablet

Title

Pregaben 50 mg Capsule

Categories

  • Anticonvulsant
  • Pain Management
  • Neuropathic Pain
  • Seizure Disorders
  • Fibromyalgia

Description

Pregaben is indicated for neuropathic pain associated with diabetic peripheral neuropathy (DPN), postherpetic neuralgia (PHN), adjunctive therapy for the treatment of partial-onset seizures in patients 1 month of age and older, fibromyalgia, and neuropathic pain associated with spinal cord injury.

Dimensions

N/A

Color Options

  • N/A

Functions

  • Pain Relief
  • Seizure Control
  • Neurological Symptom Management

Materials

  • Active Ingredient: Pregabalin
  • Tablet Composition: CR Capsule with Pregabalin

Technical Specifications

  • Maximum Recommended Dose: 100 mg three times a day or 330 mg once daily (Pregabalin), 660 mg once daily (Pregabalin CR capsule)
  • Dosage Forms:
    • Tablets
    • Extended-Release Capsules
  • Route of Administration: Oral
  • Dosage Adjustment: Based on Efficacy and Tolerability
  • Storage Conditions: Below 30°C, Protected from Light & Moisture

Design Elements

  • Chemical Structure
  • Molecular Formula: C8H17NO2
  • Chemical Structure Image

Usability Features

  • Administration: Taken with or without food (Pregabalin), Administered after an evening meal (Pregabalin CR tablet)
  • Dosing Instructions: Gradual Tapering Over a Minimum of 1 Week for Discontinuation
  • Dosage Conversion:
    • Pregabalin Tablet Daily Dose:
      • 75 mg/daily
      • 150 mg/daily
      • 225 mg/daily
      • 300 mg/daily
      • 450 mg/daily
      • 600 mg/daily
    • Pregabalin CR Capsule Capsule Dose:
      • 82.5 mg/day
      • 165 mg/day
      • 247.5 mg/day
      • 330 mg/day
      • 495 mg/day
      • 660 mg/day

Side Effects

  • Common Adult Side Effects:
    • Dizziness
    • Somnolence
    • Dry Mouth
    • Edema
    • Blurred Vision
    • Weight Gain
    • Difficulty with Concentration/Attention
  • Common Pediatric Side Effects:
    • Increased Weight
    • Increased Appetite

Pregnancy & Lactation

  • Pregnancy: No Adequate and Well-Controlled Studies, Potential Risk to Fetus
  • Lactation: Small Amounts Detected in Milk, Breastfeeding Not Recommended

Pharmacology

  • Mechanism of Action: Binds to the alpha2-delta site in central nervous system tissues, with anti-nociceptive and antiseizure effects

Interaction

  • Drug Interaction with Medication: Unlikely to be Involved in Significant Pharmacokinetic Drug Interactions
  • Drug Interaction with Food and Others: Not Applicable

Contraindications

  • Known Hypersensitivity to Pregabalin or Any of its Components

Precautions & Warnings

  • Adverse Reactions:
    • Angioedema
    • Hypersensitivity Reactions
    • Increased Risk of Suicidal Thoughts or Behavior
    • Respiratory Depression
    • Dizziness and Somnolence
    • Peripheral Edema
  • Cautions: When Coadministering with Thiazolidinedione Antidiabetic Agents

Use in Special Populations

  • Children and Adolescents: Safety and Effectiveness Not Established for Various Indications
  • Pediatric Use of Pregaben Extended-Release Tablet: Safety and Effectiveness Not Established

Overdose Effects

  • Signs and Symptoms:
    • Reduced Consciousness
    • Depression/Anxiety
    • Confusional State
    • Agitation
    • Restlessness
    • Seizures
    • Heart Block
  • Antidote: None, General Supportive Care Indicated

Therapeutic Class

  • Adjunct Anti-Epileptic Drugs
  • Primary Anti-Epileptic Drugs

FAQs about Pregaben 50 mg Capsule

  • Typical Uses: Neurotic Pain, Shingles, Seizures, Fibromyalgia
  • Dosage Frequency: As Prescribed by Doctor
  • Instructions for Storage and Disposal: Kept in Cool Dry Place, Original Packaging, Unreachable to Children and Pets
  • Necessity of Continuous Use: Consult Doctor Before Discontinuation
  • Combination with Diazepam: Can Be Used Together
  • Potential Side Effect of Weight Gain: Due to Increased Hunger, Consult Dietician if Concerned about Weight Stability
  • Quick Tips:
    • Take as per Dose and Duration Prescribed by Doctor
    • May Cause Sleepiness, Avoid Driving or Activities Requiring Concentration
    • May Cause Blurring or Loss of Vision, Inform Doctor of Any Changes
    • Inform Doctor of Unusual Changes in Mood or Behavior
    • Do Not Stop Suddenly, Gradual Discontinuation Recommended

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