Pregaben 150 mg (Capsule)
Unit Price: ৳ 30.00 (2 x 10: ৳ 600.00)
Strip Price: ৳ 300.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Pregabalin |
| Company | Incepta pharmaceuticals ltd |
| Also available as |
Indications
- Neuropathic pain associated with diabetic peripheral neuropathy (DPN)
- Postherpetic neuralgia (PHN)
- Adjunctive therapy for the treatment of partial-onset seizures in patients 1 month of age and older
- Fibromyalgia
- Neuropathic pain associated with spinal cord injury
Pharmacology
- Structural derivative of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA)
- Binds with high affinity to the alpha2-delta site in central nervous system tissues
Dosage
- Maximum recommended dose of Pregabalin for Neuropathic pain associated with diabetic peripheral neuropathy 100 mg three times a day (300 mg/day)
- Maximum recommended dose of Pregabalin CR capsule for Neuropathic pain associated with diabetic peripheral neuropathy is 330 mg once daily
- Recommended dose range of Pregabalin for neuropathic pain associated with spinal cord injury is 150 to 600 mg/day
- Dosing of Pregabalin CR capsule should be initiated at 165 mg once daily and increased to 330 mg once daily within 1 week
Administration
- Pregabalin is taken orally and can be taken with or without food
- Pregabalin CR tablet should be administered after an evening meal and swallowed whole without splitting, crushing, or chewing
Interaction
- Pregabalin is unlikely to be involved in significant pharmacokinetic drug interactions
Contraindications
- Contraindicated in patients with known hypersensitivity to Pregabalin or any of its components
Side Effects
- Common side effects in adults include dizziness, somnolence, dry mouth, edema, blurred vision, weight gain, and thinking abnormal
- Common side effects in pediatric patients for the treatment of partial onset seizures include increased weight and increased appetite
Pregnancy & Lactation
- No adequate and well-controlled studies with pregabalin in pregnant women
- Small amounts of pregabalin have been detected in the milk of lactating women
- Breastfeeding is not recommended during treatment with pregabalin
Precautions & Warnings
- Angioedema can occur and may be associated with life-threatening respiratory compromise requiring emergency treatment
- Discontinue immediately in cases of angioedema or hypersensitivity reactions
- Increase the risk of suicidal thoughts or behavior
- Respiratory depression may occur when used with concomitant CNS depressants or in the setting of underlying respiratory impairment
- May cause dizziness and somnolence, impairing the ability to drive or operate machinery
- Increased seizure frequency or other adverse reactions may occur if rapidly discontinued
Use in Special Populations
- Safety and effectiveness in pediatric patients not established for certain conditions
- Safety and effectiveness of Pregaben extended-release tablet in pediatric patients not established
Overdose Effects
- Signs and symptoms include reduced consciousness, depression/anxiety, confusional state, agitation, restlessness, seizures, and heart block
- No specific antidote
Therapeutic Class
- Adjunct anti-epileptic drugs
- Primary anti-epileptic drugs
Storage Conditions
- Should be kept in a cool & dry place (below 30°C), protected from light & moisture
- Keep out of the reach of children
Chemical Structure
- Molecular Formula: C8H17NO2
- Chemical Structure is a derivative of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA)
Common Questions
- What is Pregaben 150 mg Capsule?
- How long do I need to use Pregaben 150 mg Capsule before I see improvement in my condition?
- At what frequency do I need to use Pregaben 150 mg Capsule?
- Should I use Pregaben 150 mg Capsule empty stomach, before food or after food?
- What are the instructions for the storage and disposal of Pregaben 150 mg Capsule?
- Does Pregaben 150 mg Capsule work in the same way for each disease?
- How long do I need to take Pregaben 150 mg Capsule?
- Is it necessary to continue taking Pregaben 150 mg Capsule even if I feel fine?
- Can I take Diazepam and Pregaben 150 mg Capsule together?
- Can the use of Pregaben 150 mg Capsule cause weight gain?
- Pregaben 150 mg Capsule should be taken as per the dose and duration prescribed by your doctor
- Pregaben 150 mg Capsule may cause sleepiness
- Pregaben 150 mg Capsule may cause blurring or loss of vision
- Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts or behavior
- Do not stop taking Pregaben 150 mg Capsule suddenly without talking to your doctor