Pregan 50 mg (Capsule)
Unit Price: ৳ 14.00 (3 x 10: ৳ 420.00)
Strip Price: ৳ 140.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Pregabalin |
| Company | Navana pharmaceuticals ltd |
| Also available as |
Indications
- Neuropathic pain associated with diabetic peripheral neuropathy (DPN)
- Postherpetic neuralgia (PHN)
- Adjunctive therapy for the treatment of partial-onset seizures in patients 1 month of age and older
- Fibromyalgia
- Neuropathic pain associated with spinal cord injury
Pharmacology
- Structural derivative of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA)
- Binds with high affinity to the alpha2-delta site in central nervous system tissues
Dosage
- Maximum recommended dose of 100 mg three times a day for neuropathic pain associated with diabetic peripheral neuropathy
- Recommended dose of 75 to 150 mg two times a day for postherpetic neuralgia
- Recommended dose of 300 to 450 mg/day for the management of fibromyalgia
- Recommended dose range of 150 to 600 mg/day for neuropathic pain associated with spinal cord injury
Administration
- Oral route of administration
- Can be taken with or without food
- Pregabalin CR tablet should be administered after an evening meal
- Gradual tapering over a minimum of 1 week when discontinuing
Interaction
- Unlikely to be involved in significant pharmacokinetic drug interactions
- No significant food and other interactions
Contraindications
- Contraindicated in patients with known hypersensitivity to Pregabalin or any of its components
Side Effects
- Common side effects in adults include dizziness, somnolence, dry mouth, edema, blurred vision, weight gain, and thinking abnormal
- Common side effects in pediatric patients include increased weight and increased appetite
Pregnancy & Lactation
- No adequate and well-controlled studies in pregnant women
- Small amounts detected in the milk of lactating women
- Breastfeeding not recommended due to potential risk of tumorigenicity
Precautions & Warnings
- Risk of angioedema, hypersensitivity reactions, and suicidal thoughts or behavior
- Respiratory depression may occur with concomitant CNS depressants
- May cause dizziness, somnolence, and peripheral edema
- Caution needed when coadministering with thiazolidinedione antidiabetic agents
Use in Special Populations
- Safety and effectiveness not established in pediatric patients for certain indications
- Safety and effectiveness of Pregan extended-release tablet not established in pediatric patients
Overdose Effects
- Symptoms include reduced consciousness, depression/anxiety, confusional state, agitation, restlessness, seizures, and heart block
- No specific antidote
Therapeutic Class
- Adjunct anti-epileptic drugs
- Primary anti-epileptic drugs
Storage Conditions
- Keep in a cool & dry place below 30°C, protected from light & moisture
- Keep out of the reach of children
Chemical Structure
- Molecular Formula: C8H17NO2
Common Questions
- What is Pregan 50 mg Capsule?
- How long do I need to use Pregan 50 mg Capsule before I see improvement in my condition?
- At what frequency do I need to use Pregan 50 mg Capsule?
- Should I use Pregan 50 mg Capsule empty stomach, before food or after food?
- What are the instructions for the storage and disposal of Pregan 50 mg Capsule?
- Does Pregan 50 mg Capsule work in the same way for each disease?
- How long do I need to take Pregan 50 mg Capsule?
- Is it necessary to continue taking Pregan 50 mg Capsule even if I feel fine?
- Can I take Diazepam and Pregan 50 mg Capsule together?
- Can the use of Pregan 50 mg Capsule cause weight gain?
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