Prelica 75 mg (Capsule)
Medicine Details
| Category | Details |
|---|---|
| Generic | Pregabalin |
| Company | Radiant pharmaceuticals ltd |
| Also available as |
Indications
- Neuropathic pain associated with diabetic peripheral neuropathy (DPN)
- Postherpetic neuralgia (PHN)
- Adjunctive therapy for the treatment of partial-onset seizures in patients 1 month of age and older
- Fibromyalgia
- Neuropathic pain associated with spinal cord injury
Pharmacology
Pregabalin is a structural derivative of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA). It binds with high affinity to the alpha2-delta site in central nervous system tissues, which may be involved in its effects on pain and seizures.
Dosage
Dosage varies based on the specific condition being treated, with different recommended starting doses and maximum doses for different indications.
Administration
- Route of administration: Oral
- Instructions: Pregabalin CR tablet should be swallowed whole after an evening meal and should not be split, crushed or chewed. When discontinuing, it should be gradually tapered over a minimum of 1 week.
Drug interaction
Unlikely to have significant pharmacokinetic drug interactions.
Contraindications
Contraindicated in patients with known hypersensitivity to Pregabalin or any of its components.
Side Effects
- Dizziness
- Somnolence
- Dry mouth
- Edema
- Blurred vision
- Weight gain
- Difficulty with concentration/attention
- Increased weight
- Increased appetite
Pregnancy & Lactation
- Pregnancy: No adequate and well-controlled studies, potential risk to fetus
- Lactation: Not recommended due to potential risk of tumorigenicity
Precautions & Warnings
- Angioedema may occur and should be immediately addressed
- Discontinue immediately in case of hypersensitivity reactions
- Increased risk of suicidal thoughts or behavior
- May cause respiratory depression when used with concomitant CNS depressants or in the setting of underlying respiratory impairment
- May cause dizziness and somnolence
- Increased seizure frequency or other adverse reactions may occur if rapidly discontinued
- May cause peripheral edema
- Exercise caution when coadministering with thiazolidinedione antidiabetic agents
Use in Special Populations
- Children and adolescents: Safety and effectiveness not established for certain indications and age groups
Overdose Effects
Signs and symptoms include reduced consciousness, depression/anxiety, confusional state, agitation, restlessness, seizures, and heart block. There is no specific antidote.
Therapeutic Class
Adjunct anti-epileptic drugs, Primary anti-epileptic drugs
Storage Conditions
Keep in a cool & dry place (below 30°C), protected from light & moisture. Keep out of the reach of children.
Chemical Structure
- Molecular Formula: C8H17NO2
- Chemical Structure Image: https://medex.com.bd/storage/res/g-res-919-pregabalin-chemical-structure-dKjKzfuVRrNkwNMBalNK.svg
Common Questions
- What is Prelica 75 mg Capsule?
- How long do I need to use Prelica 75 mg Capsule before I see improvement in my condition?
- At what frequency do I need to use Prelica 75 mg Capsule?
- Should I use Prelica 75 mg Capsule empty stomach, before food or after food?
- What are the instructions for the storage and disposal of Prelica 75 mg Capsule?
- Does Prelica 75 mg Capsule work in the same way for each disease?
- How long do I need to take Prelica 75 mg Capsule?
- Is it necessary to continue taking Prelica 75 mg Capsule even if I feel fine?
- Can I take Diazepam and Prelica 75 mg Capsule together?
- Can the use of Prelica 75 mg Capsule cause weight gain?
- Quick Tips