Prelin 50 mg (Capsule)

Unit Price: ৳ 13.00 (2 x 10: ৳ 260.00)
Strip Price: ৳ 130.00

Medicine Details

Indications

  • Neuropathic pain associated with diabetic peripheral neuropathy (DPN)
  • Postherpetic neuralgia (PHN)
  • Adjunctive therapy for the treatment of partial-onset seizures in patients 1 month of age and older
  • Fibromyalgia
  • Neuropathic pain associated with spinal cord injury

Pharmacology

Pregabalin is a structural derivative of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA). It binds with high affinity to the alpha2-delta site in central nervous system tissues.

Dosage

  • Neuropathic pain associated with diabetic peripheral neuropathy in adults (DPN): 50-300 mg/day
  • Postherpetic neuralgia in adults (PHN): 75-300 mg/day
  • Management of fibromyalgia in adults: 300-450 mg/day
  • Neuropathic pain associated with spinal cord injury in adults: 150-600 mg/day

Administration

  • Route of administration: Oral
  • Special administration for Pregabalin CR tablet: Administer after an evening meal, swallow whole

Interaction

  • Drug interaction with medication: Unlikely to cause significant pharmacokinetic drug interactions

Contraindications

Contraindicated in patients with known hypersensitivity to Pregabalin or any of its components

Side Effects

  • Dizziness
  • Somnolence
  • Dry mouth
  • Edema
  • Blurred vision
  • Weight gain
  • Difficulty with concentration/attention (primarily)

Pregnancy & Lactation

  • Pregnancy: No adequate and well-controlled studies
  • Lactation: Small amounts detected in the milk of lactating women, not recommended during treatment

Precautions & Warnings

  • Angioedema can occur and may be associated with life-threatening respiratory compromise
  • Discontinue immediately in case of hypersensitivity reactions
  • Increased risk of suicidal thoughts or behavior
  • May cause dizziness and somnolence, impairing ability to drive or operate machinery
  • May cause peripheral edema, use caution when coadministering with thiazolidinedione antidiabetic agents

Use in Special Populations

Safety and effectiveness not established in pediatric patients for certain indications

Overdose Effects

Reduced consciousness, depression/anxiety, seizures, heart block; no specific antidote

Therapeutic Class

  • Adjunct anti-epileptic drugs
  • Primary anti-epileptic drugs

Storage Conditions

Keep in a cool, dry place (below 30°C), protected from light and moisture

Chemical Structure

  • Molecular Formula: C8H17NO2
  • Chemical Structure Image: https://medex.com.bd/storage/res/g-res-919-pregabalin-chemical-structure-dKjKzfuVRrNkwNMBalNK.svg

Common Questions

  • What is Prelin 50 mg Capsule?
  • How long do I need to use Prelin 50 mg Capsule for improvement?
  • At what frequency do I need to use Prelin 50 mg Capsule?
  • Instructions for storage and disposal
  • Does Prelin 50 mg Capsule work the same way for each disease?
  • How long do I need to take Prelin 50 mg Capsule?
  • Is it necessary to continue taking Prelin 50 mg Capsule even if I feel fine?
  • Can I take Diazepam and Prelin 50 mg Capsule together?
  • Can the use of Prelin 50 mg Capsule cause weight gain?

Quick Tips

  • Take as prescribed by your doctor
  • May cause sleepiness, do not drive or operate machinery until effects are known
  • May cause blurring or loss of vision, inform your doctor immediately
  • Do not stop suddenly without consulting your doctor

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